What do systematic reviews say?

Multi‐component intervention vs other treatments/routine care

It is very uncertain whether multi‐component intervention changes adverse events: number of people experiencing an AE compared with other intervention or routine, usual care or control treatment (very low certainty).

• Digital interventions for the management of chronic obstructive pulmonary disease 2021 · Cochrane Headline outcomes only
  OR 1.07 [0.51, 2.25]
  1 study · 166 participants
  Very low

Multi‐component intervention vs other treatments/routine care

Multi‐component intervention showed no clear difference in adverse events: number of people experiencing a serious adverse event compared with other intervention or routine, usual care or control treatment (low certainty).

• Digital interventions for the management of chronic obstructive pulmonary disease 2021 · Cochrane Headline outcomes only
  OR 0.85 [0.55, 1.34]
  1 study · 319 participants
  Low

Multi‐component intervention vs other treatments/routine care

• Digital interventions for the management of chronic obstructive pulmonary disease 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 20 participants
  Very low

Multi‐component intervention vs other treatments/routine care

• Digital interventions for the management of chronic obstructive pulmonary disease 2021 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 241 participants
  Very low

Multi‐component intervention vs other treatments/routine care

It is very uncertain whether multi‐component intervention changes exacerbations: number of people experiencing at least one exacerbation compared with other intervention or routine, usual care or control treatment (very low certainty).

• Digital interventions for the management of chronic obstructive pulmonary disease 2021 · Cochrane Headline outcomes only
  OR 0.86 [0.58, 1.28]
  2 studies · 485 participants
  Very low

Self‐management interventions vs usual care

It is very uncertain whether self‐management interventions changes respiratory‐related hospital admissions compared with usual care (very low certainty).

• Self‐management interventions for people with chronic obstructive pulmonary disease 2022 · Cochrane Headline outcomes only
  OR 0.75 [0.57, 0.98]
  3263 participants
  Very low
• Self‐management interventions including action plans for exacerbations versus usual care in patients with chronic… 2017 · Cochrane Headline outcomes only
  OR 0.69 [0.51, 0.94]
  14 studies · 3157 participants
  Moderate

Self‐management interventions vs usual care

Self‐management interventions showed no clear difference in respiratory‐related mortality compared with usual care (low certainty).

• Self‐management interventions for people with chronic obstructive pulmonary disease 2022 · Cochrane Headline outcomes only
  OR 1.7 [0.89, 3.26]
  1572 participants
  Low
• Self‐management interventions including action plans for exacerbations versus usual care in patients with chronic… 2017 · Cochrane Headline outcomes only
  OR 1.94 [1.2, 3.13]
  7 studies · 1219 participants
  Very low

Self‐management interventions vs usual care

Self‐management interventions showed no clear difference in all‐cause mortality compared with usual care (low certainty).

• Self‐management interventions for people with chronic obstructive pulmonary disease 2022 · Cochrane Headline outcomes only
  OR 0.86 [0.59, 1.26]
  5719 participants
  Low
• Self‐management interventions including action plans for exacerbations versus usual care in patients with chronic… 2017 · Cochrane Headline outcomes only
  OR 1.06 [0.71, 1.59]
  16 studies · 3296 participants
  Moderate

Self‐management interventions vs usual care

Self‐management interventions showed no clear difference in all‐cause hospital admissions compared with usual care (moderate certainty).

• Self‐management interventions for people with chronic obstructive pulmonary disease 2022 · Cochrane Headline outcomes only
  OR 0.88 [0.71, 1.08]
  2633 participants
  Moderate
• Self‐management interventions including action plans for exacerbations versus usual care in patients with chronic… 2017 · Cochrane Headline outcomes only
  OR 0.74 [0.54, 1.03]
  10 studies · 2467 participants
  Moderate

Self‐management interventions vs usual care

• Self‐management interventions for people with chronic obstructive pulmonary disease 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1401 participants
  Moderate
• Self‐management interventions including action plans for exacerbations versus usual care in patients with chronic… 2017 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 740 participants
  Moderate

Self‐management interventions vs usual care

• Self‐management interventions for people with chronic obstructive pulmonary disease 2022 · Cochrane Headline outcomes only
  no estimate extracted
  2778 participants
  Low

Self‐management interventions vs usual care

• Self‐management interventions for people with chronic obstructive pulmonary disease 2022 · Cochrane Headline outcomes only
  no estimate extracted
  356 participants
  Low

Self‐management interventions vs usual care

• Self‐management interventions for people with chronic obstructive pulmonary disease 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1939 participants
  Low

Self‐management interventions vs usual care

• Self‐management interventions for people with chronic obstructive pulmonary disease 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1647 participants
  Moderate

Integrated disease management interventions vs usual care

• Integrated disease management interventions for patients with chronic obstructive pulmonary disease 2021 · Cochrane Headline outcomes only
  no estimate extracted
  18 studies · 4321 participants
  Moderate

Integrated disease management interventions vs usual care

• Integrated disease management interventions for patients with chronic obstructive pulmonary disease 2021 · Cochrane Headline outcomes only
  no estimate extracted
  13 studies · 2071 participants
  Moderate

Integrated disease management interventions vs usual care

Integrated disease management interventions leads to lower respiratory‐related hospital admissions compared with usual care (high certainty).

• Integrated disease management interventions for patients with chronic obstructive pulmonary disease 2021 · Cochrane Headline outcomes only
  OR 0.64 [0.5, 0.81]
  15 studies · 4207 participants
  High

Integrated disease management interventions vs usual care

Integrated disease management interventions probably leads to lower hospital admissions, all causes compared with usual care (moderate certainty).

• Integrated disease management interventions for patients with chronic obstructive pulmonary disease 2021 · Cochrane Headline outcomes only
  OR 0.75 [0.57, 0.98]
  10 studies · 9030 participants
  Moderate

Integrated disease management interventions vs usual care

• Integrated disease management interventions for patients with chronic obstructive pulmonary disease 2021 · Cochrane Headline outcomes only
  no estimate extracted
  14 studies · 3563 participants
  Moderate

Integrated disease management interventions vs usual care

Integrated disease management interventions probably leads to lower ED visits compared with usual care (moderate certainty).

• Integrated disease management interventions for patients with chronic obstructive pulmonary disease 2021 · Cochrane Headline outcomes only
  OR 0.69 [0.5, 0.93]
  9 studies · 8791 participants
  Moderate