Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,486 questions · 2,727 findings · 268 reviews

No studies found 600 · 22%GRADE not reported 229 · 8.4%Very low 789 · 28.9%Low 707 · 25.9%Moderate 314 · 11.5%High 88 · 3.2%

Any intervention vs steroid alone or plus levofloxacin

Proportion of participants who discontinued medication and did not develop rebound SEI within 21 days (higher is favored) · epidemic keratoconjunctivitis

It is very uncertain whether any intervention changes proportion of participants who discontinued medication and did not… compared with steroid alone or plus levofloxacin (very low certainty).

1 finding from 1 review

Any intervention vs steroid alone or plus levofloxacin

Proportion of initially unaffected fellow eyes that had signs/symptoms of infection within 7 days of onset of signs/symptoms in the first eye (lower is favored) · epidemic keratoconjunctivitis

The review found no eligible studies for this question.

1 finding from 1 review

Any intervention vs artificial tears or saline

Proportion of participants in whose eyes SEIs had developed within 30 days of treatment initiation (lower is favored) · epidemic keratoconjunctivitis

It is very uncertain whether any intervention changes proportion of participants in whose eyes SEIs had developed within… compared with artificial tears or saline (very low certainty).

1 finding from 1 review

Any intervention vs artificial tears or saline

Proportion of participants in whose eyes SEI had disappeared within 21 days of treatment (higher is favored) · epidemic keratoconjunctivitis

It is very uncertain whether any intervention changes proportion of participants in whose eyes SEI had disappeared within… compared with artificial tears or saline (very low certainty).

1 finding from 1 review