Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,486 questions · 2,727 findings · 268 reviews

No studies found 600 · 22%GRADE not reported 229 · 8.4%Very low 789 · 28.9%Low 707 · 25.9%Moderate 314 · 11.5%High 88 · 3.2%

Lay health worker‐ vs enhanced usual care

Clinical recovery ‐ harmful or dependent alcohol use (1 to 6 months post intervention) Defined by AUDIT score < 8 (RR > 1 denotes higher likelihood of recovery) · adult patients with alcohol dependence

It is very uncertain whether lay health worker‐led interventions changes clinical recovery ‐ harmful or dependent alcohol use (1 to 6 months… compared with enhanced usual care (very low certainty).

1 finding from 1 review

Lay health worker‐ vs enhanced usual care

Clinical symptoms ‐ alcohol use (1 to 6 months post intervention) · adult patients with alcohol dependence

It is very uncertain whether lay health worker‐led interventions changes clinical symptoms ‐ alcohol use (1 to 6 months post intervention) compared with enhanced usual care (very low certainty).

1 finding from 1 review

Lay health worker‐ vs enhanced usual care

Clinical symptoms ‐ depression (1 to 6 months post intervention) · adult patients with alcohol dependence

It is very uncertain whether lay health worker‐led interventions changes clinical symptoms ‐ depression (1 to 6 months post intervention) compared with enhanced usual care (very low certainty).

1 finding from 1 review

Lay health worker‐ vs enhanced usual care

Functional impairment · adult patients with alcohol dependence

It is very uncertain whether lay health worker‐led interventions changes functional impairment (1 to 6 months post intervention) compared with enhanced usual care (very low certainty).

1 finding from 1 review

Lay health worker‐ vs enhanced usual care

Service utilisation ‐ Unplanned hospitalisation in past 12 months (RR > 1 denotes higher risk of hospitalisation) · adult patients with alcohol dependence

It is very uncertain whether lay health worker‐led interventions changes service utilisation ‐ Unplanned hospitalisation in past 12 months… compared with enhanced usual care (very low certainty).

1 finding from 1 review

Lay health worker‐ vs enhanced usual care

Adverse events ‐ death in past 12 months (RR > 1 denotes higher risk of death) · adult patients with alcohol dependence

It is very uncertain whether lay health worker‐led interventions changes adverse events ‐ death in past 12 months (RR > 1 denotes higher risk… compared with enhanced usual care (very low certainty).

1 finding from 1 review

Complementary therapy interventions vs usual care or no treatment

Number of participants continent after treatment · people with stroke and urinary incontinence

Complementary therapy interventions may leads to higher number of participants continent after treatment compared with usual care or no treatment (low certainty).

1 finding from 1 review

Physical conditioning interventions vs usual care

Proportion of participants at work in the extended long term (≥ 5 years) · patients with coronary heart disease

Physical conditioning interventions may leads to higher proportion of participants at work in the extended long term (≥ 5… compared with usual care (low certainty).

1 finding from 1 review