Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

536 questions · 579 findings · 94 reviews

No studies found 151 · 26.1%GRADE not reported 52 · 9%Very low 182 · 31.4%Low 120 · 20.7%Moderate 52 · 9%High 22 · 3.8%

Any antimicrobial mouthwash and/or nasal spray (alone or in combination), at any concentration, delivered to healthcare workers, with or without the same intervention given to the patients with COVID-19 vs No treatment or saline or water

Anosmia (or disturbance in sense of smell) · Healthcare workers (HCWs) treating patients with suspected or confirmed COVID-19 infection

The review found no eligible studies for this question.

1 finding from 1 review

Any antimicrobial mouthwash and/or nasal spray (alone or in combination), at any concentration, delivered to healthcare workers, with or without the same intervention given to the patients with COVID-19 vs No treatment or saline or water

Viral content of aerosol · Healthcare workers (HCWs) treating patients with suspected or confirmed COVID-19 infection

The review found no eligible studies for this question.

1 finding from 1 review

Any antimicrobial mouthwash and/or nasal spray (alone or in combination), at any concentration, delivered to healthcare workers, with or without the same intervention given to the patients with COVID-19 vs No treatment or saline or water

Changes in microbiome in oral cavity, nasal cavity, oro- or nasopharynx · Healthcare workers (HCWs) treating patients with suspected or confirmed COVID-19 infection

The review found no eligible studies for this question.

1 finding from 1 review

Any antimicrobial mouthwash and/or nasal spray (alone or in combination), at any concentration, delivered to healthcare workers, with or without the same intervention given to the patients with COVID-19 vs No treatment or saline or water

Incidence of symptomatic or test-positive COVID-19 infection in HCWs · Healthcare workers (HCWs) treating patients with suspected or confirmed COVID-19 infection

The review found no eligible studies for this question.

1 finding from 1 review

Any antimicrobial mouthwash and/or nasal spray (alone or in combination), at any concentration, delivered to healthcare workers, with or without the same intervention given to the patients with COVID-19 vs No treatment or saline or water

Other adverse events (allergy, irritation/burning of nasal, oral or oropharyngeal mucosa, long-term staining of mucous membranes or teeth, accidental ingestion) · Healthcare workers (HCWs) treating patients with suspected or confirmed COVID-19 infection

The review found no eligible studies for this question.

1 finding from 1 review

Any Psychosocial intervention plus pharm vs pharm standard

Retention in treatment · patients with treatment of opioid dependence

Any Psychosocial intervention plus pharm showed no clear difference in retention in treatment Objective compared with pharm standard (high certainty).

1 finding from 1 review

Any Psychosocial intervention plus pharm vs pharm standard

Opioid abstinence objective · patients with treatment of opioid dependence

Any Psychosocial intervention plus pharm showed no clear difference in opioid abstinence objective compared with pharm standard (high certainty).

1 finding from 1 review

Any Psychosocial intervention plus pharm vs pharm standard

Number of participants still in treatment at the end of · patients with treatment of opioid dependence

Any Psychosocial intervention plus pharm showed no clear difference in number of participants still in treatment at the end of compared with pharm standard (high certainty).

1 finding from 1 review

Any Psychosocial intervention plus pharm vs pharm standard

Abstinence · patients with treatment of opioid dependence

Any Psychosocial intervention plus pharm showed no clear difference in number of participants abstinent at the end of compared with pharm standard (high certainty).

1 finding from 1 review