What do systematic reviews say?

Increased vs stable doses of inhaled corticosteroids

Increased showed no clear difference in treatment failure: need for systemic corticosteroids (ITT) compared with stable doses of inhaled corticosteroids (moderate certainty).

• Increased versus stable doses of inhaled corticosteroids for exacerbations of chronic asthma in adults and children 2022 · Cochrane Headline outcomes only
  OR 0.97 [0.76, 1.25]
  8 studies · 1774 participants
  Moderate

Increased vs stable doses of inhaled corticosteroids

It is very uncertain whether increased changes treatment failure: need for systemic corticosteroids (of those… compared with stable doses of inhaled corticosteroids (very low certainty).

• Increased versus stable doses of inhaled corticosteroids for exacerbations of chronic asthma in adults and children 2022 · Cochrane Headline outcomes only
  OR 0.84 [0.54, 1.3]
  7 studies · 766 participants
  Very low

Increased vs stable doses of inhaled corticosteroids

The review found no eligible studies for this question.

• Increased versus stable doses of inhaled corticosteroids for exacerbations of chronic asthma in adults and children 2022 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Increased vs stable doses of inhaled corticosteroids

Increased showed no clear difference in unscheduled physician visits 44 weeks compared with stable doses of inhaled corticosteroids (low certainty).

• Increased versus stable doses of inhaled corticosteroids for exacerbations of chronic asthma in adults and children 2022 · Cochrane Headline outcomes only
  OR 0.96 [0.66, 1.41]
  3 studies · 931 participants
  Low

Increased vs stable doses of inhaled corticosteroids

• Increased versus stable doses of inhaled corticosteroids for exacerbations of chronic asthma in adults and children 2022 · Cochrane Headline outcomes only
  0.5 [0.16, 1.56]
  4 studies · 704 participants
  Very low

Increased vs stable doses of inhaled corticosteroids

It is very uncertain whether increased changes serious adverse events 48 weeks compared with stable doses of inhaled corticosteroids (very low certainty).

• Increased versus stable doses of inhaled corticosteroids for exacerbations of chronic asthma in adults and children 2022 · Cochrane Headline outcomes only
  OR 1.69 [0.77, 3.71]
  2 studies · 394 participants
  Very low

Increased vs stable doses of inhaled corticosteroids

It is very uncertain whether increased changes non‐serious adverse events 43 weeks compared with stable doses of inhaled corticosteroids (very low certainty).

• Increased versus stable doses of inhaled corticosteroids for exacerbations of chronic asthma in adults and children 2022 · Cochrane Headline outcomes only
  OR 2.15 [0.68, 6.73]
  2 studies · 142 participants
  Very low

Increased vs stable doses of inhaled corticosteroids

• Increased versus stable doses of inhaled corticosteroids for exacerbations of chronic asthma in adults and children 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 207 participants
  Low