Immediate treatment leads to higher five‐year immediate remission after randomisation compared with controls (high certainty).
Immediate treatment leads to lower seizure recurrence at 5 years after randomisation compared with controls (high certainty).
Immediate treatment showed no clear difference in five‐year remission at any time after randomisation compared with controls (high certainty).
Immediate treatment leads to lower seizure recurrence at 1 year after randomisation compared with controls (high certainty).
Immediate treatment showed no clear difference in mortality at the end of the compared with controls (high certainty).
Immediate treatment probably leads to higher adverse events (control ‐ deferred treatment) compared with controls (moderate certainty).
Immediate treatment may leads to higher adverse events (control ‐ no treatment) compared with controls (low certainty).
Immediate treatment probably leads to higher adverse events (control ‐ placebo) compared with controls (moderate certainty).