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What do systematic reviews say?

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Evidence found and GRADE certainty

4 questions · 6 findings · 1 reviews · Headline outcomes only

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No studies found 5 · 83.3%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 1 · 16.7%High 0 · 0%

Ibuprofen vs morphine

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · children with acute postoperative pain

The review found no eligible studies for this question.

2 findings from 1 review

Ibuprofen vs morphine

Adverse events (reported in the first 7 days after the procedure) · children with acute postoperative pain

Ibuprofen probably leads to lower adverse events (reported in the first 7 days after the procedure) compared with morphine (moderate certainty).

1 finding from 1 review

Ibuprofen vs morphine

Serious adverse events, defined as any medical event at any dose that results in death, is life‐threatening, requires hospitalisation (or prolongation of existing hospitalisation) or results in permanent damage or disability (FDA 2016) · children with acute postoperative pain

The review found no eligible studies for this question.

1 finding from 1 review