Preimplantation complications · Patients who have had radiotherapy and who have missing teeth that require replacement with osseointegrated dental implants
Hyperbaric oxygen (HBO) therapy led to lower preimplantation complications compared with no HBO therapy; GRADE not reported.
1 finding from 1 review
Analysis 1.1 (Dichotomous outcomes: Preimplantation complications): Risk Ratio (M-H, Fixed, 95% CI), totals not selected; not estimable (no events in either arm).
1 study · 24 participants
GRADE not reported
Prosthetic failure (2 years) · Patients who have had radiotherapy and who have missing teeth that require replacement with osseointegrated dental implants
It is very uncertain whether hyperbaric oxygen (HBO) therapy changes prosthetic failure compared with no HBO therapy (very low certainty).
1 finding from 1 review
Marginal bone level change · Patients who have had radiotherapy and who have missing teeth that require replacement with osseointegrated dental implants
1 finding from 1 review
Overall denture satisfaction (0-10 scale) · Patients who have had radiotherapy and who have missing teeth that require replacement with osseointegrated dental implants
Hyperbaric oxygen (HBO) therapy showed no clear difference in patient satisfaction (overall denture satisfaction) compared with no HBO therapy; GRADE not reported.
1 finding from 1 review
Analysis 1.2 (Overall denture satisfaction): Mean Difference (IV, Fixed, 95% CI), totals not selected (value not displayed).
1 study · 17 participants
GRADE not reported
Cost‐effectiveness · Patients who have had radiotherapy and who have missing teeth that require replacement with osseointegrated dental implants
The review found no eligible studies for this question.
1 finding from 1 review
Implant failure · Patients who have had radiotherapy and who have missing teeth that require replacement with osseointegrated dental implants
Hyperbaric oxygen (HBO) therapy showed no clear difference in implant failure compared with no HBO therapy; GRADE not reported.
1 finding from 1 review
Postimplantation complications · Patients who have had radiotherapy and who have missing teeth that require replacement with osseointegrated dental implants
Hyperbaric oxygen (HBO) therapy showed no clear difference in postimplantation complications compared with no HBO therapy; GRADE not reported.
1 finding from 1 review
Incidence of ORN · Adults with head and neck cancer undergoing curative or adjuvant radiotherapy (at risk of osteoradionecrosis of the jaws)
It is very uncertain whether hyperbaric oxygen therapy (HBO) following extractions changes incidence of ORN compared with perioperative antibiotic prophylaxis (penicillin G) following… (very low certainty).
1 finding from 1 review
Adverse effects · Adults with head and neck cancer undergoing curative or adjuvant radiotherapy (at risk of osteoradionecrosis of the jaws)
1 finding from 1 review
Adverse effects were an outcome of interest in the study conducting this comparison, however no mention was made of the presence or absence of any adverse events
1 study · 74 participants
Very low
All‐cause mortality · People undergoing radiation therapy for head and neck cancer
Hyperbaric oxygen leads to lower mortality compared with air breathing to enhance the effectiveness of radiotherapy (high certainty).
1 finding from 1 review
Failure of local tumour control ‐ not reported · People undergoing radiation therapy for head and neck cancer
Hyperbaric oxygen probably leads to lower failure of local tumour control (local control) compared with air breathing to enhance the effectiveness of radiotherapy (moderate certainty).
1 finding from 1 review
Local recurrence · People undergoing radiation therapy for head and neck cancer
Hyperbaric oxygen leads to lower local recurrence (recurrence ) compared with air breathing to enhance the effectiveness of radiotherapy (high certainty).
1 finding from 1 review
Metastasis · People undergoing radiation therapy for head and neck cancer
Hyperbaric oxygen showed no clear difference in metastasis compared with air breathing to enhance the effectiveness of radiotherapy (moderate certainty).
1 finding from 1 review
Quality of life ‐ not reported · People undergoing radiation therapy for head and neck cancer
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse effects · People undergoing radiation therapy for head and neck cancer
Hyperbaric oxygen probably leads to higher adverse effects compared with air breathing to enhance the effectiveness of radiotherapy (moderate certainty).
1 finding from 1 review
Death at 1 year · any person with radiation tissue injury arising later than 6 months after irradiation (LRTI), including dysfunction or necrosis of any…
Hyperbaric oxygen therapy (HBOT) showed no clear difference in death at 1 year compared with control without HBOT (low certainty).
1 finding from 1 review
Complete or substantial improvement of condition · any person with radiation tissue injury arising later than 6 months after irradiation (LRTI), including dysfunction or necrosis of any…
Hyperbaric oxygen therapy (HBOT) may leads to higher complete or substantial improvement of condition compared with control without HBOT (low certainty).
1 finding from 1 review
Visual disturbances · any person with radiation tissue injury arising later than 6 months after irradiation (LRTI), including dysfunction or necrosis of any…
Hyperbaric oxygen therapy (HBOT) leads to higher visual disturbances compared with control without HBOT (high certainty).
1 finding from 1 review
Otic barotrauma · any person with radiation tissue injury arising later than 6 months after irradiation (LRTI), including dysfunction or necrosis of any…
Hyperbaric oxygen therapy (HBOT) leads to higher otic barotrauma compared with control without HBOT (high certainty).
1 finding from 1 review
Wound dehiscence · any person with osteoradionecrosis of the jaw or at risk of osteoradionecrosis of the jaw
Hyperbaric oxygen therapy (HBOT) may leads to lower wound dehiscence compared with control without HBOT (low certainty).
1 finding from 1 review