Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

59 questions · 59 findings · 3 reviews

No studies found 23 · 39%GRADE not reported 4 · 6.8%Very low 25 · 42.4%Low 6 · 10.2%Moderate 1 · 1.7%High 0 · 0%

Hyaluronic acid gel (brushing) vs Chlorhexidine, 0.2% to 2% (solution or gel)

Marginal bleeding · Adults with dental implants and healthy peri-implant soft tissues at baseline

Hyaluronic acid gel (brushing) showed no clear difference in marginal bleeding compared with chlorhexidine gel (brushing); GRADE not reported.

1 finding from 1 review

Hyaluronic acid gel (brushing) vs Chlorhexidine, 0.2% to 2% (solution or gel)

Plaque · Adults with dental implants and healthy peri-implant soft tissues at baseline

Hyaluronic acid gel (brushing) showed no clear difference in plaque compared with chlorhexidine gel (brushing); GRADE not reported.

1 finding from 1 review

Hyaluronic acid gel (brushing) vs Chlorhexidine, 0.2% to 2% (solution or gel)

Change in probing pocket depth (PPD) · Adults with dental implants and healthy peri-implant soft tissues at baseline

Hyaluronic acid gel (brushing) showed no clear difference in change in probing pocket depth compared with chlorhexidine gel (brushing); GRADE not reported.

1 finding from 1 review

Hyaluronic acid‐selected sperm (HA‐ICSI) vs viscous medium containing HA (SpermSlow)

Live birth rate per woman · assisted reproduction

It is very uncertain whether hyaluronic acid‐selected sperm (HA‐ICSI) changes live birth per woman randomly assigned compared with viscous medium containing HA (SpermSlow) (very low certainty).

1 finding from 1 review

Hyaluronic acid‐selected sperm (HA‐ICSI) vs viscous medium containing HA (SpermSlow)

Miscarriage per clinical pregnancy · assisted reproduction

It is very uncertain whether hyaluronic acid‐selected sperm (HA‐ICSI) changes miscarriage per clinical pregnancy compared with viscous medium containing HA (SpermSlow) (very low certainty).

1 finding from 1 review

Hyaluronic acid‐selected sperm (HA‐ICSI) vs viscous medium containing HA (SpermSlow)

Clinical pregnancy · assisted reproduction

It is very uncertain whether hyaluronic acid‐selected sperm (HA‐ICSI) changes clinical pregnancy per woman randomly assigned compared with viscous medium containing HA (SpermSlow) (very low certainty).

1 finding from 1 review