Findings

What do systematic reviews say?

25 questions · 25 findings · 3 reviews

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No studies found 7 · 28%GRADE not reported 0 · 0%Very low 2 · 8%Low 14 · 56%Moderate 2 · 8%High 0 · 0%

Higher dose vitamin K vs lower dose vitamin K

Mortality (all infants): 0.2 mg IM versus 0.5 mg IM · preterm infants

Higher dose vitamin K showed no clear difference in mortality (all infants): 0.2 mg IM versus 0.5 mg IM compared with lower dose vitamin K (low certainty).

1 finding from 1 review

Prophylactic vitamin K for the prevention of vitamin K deficiency bleeding in preterm neonates 2018 · Cochrane Headline outcomes only
RR 2.13 [0.6, 7.51]
1 study · 65 participants
Low

A dose of vitamin D 601 IU or higher vs 600 IU or lower alone or with other nutrients

Pre‐eclampsia · women during pregnancy

A dose of vitamin D 601 IU or higher showed no clear difference in pre‐eclampsia compared with 600 IU or lower alone or with other nutrients (low certainty).

1 finding from 1 review

Regimens of vitamin D supplementation for women during pregnancy 2019 · Cochrane Headline outcomes only
RR 0.96 [0.65, 1.42]
5 studies · 1553 participants
Low

A dose of vitamin D 601 IU or higher vs 600 IU or lower alone or with other nutrients

Gestational diabetes · women during pregnancy

A dose of vitamin D 601 IU or higher probably leads to lower gestational diabetes compared with 600 IU or lower alone or with other nutrients (moderate certainty).

1 finding from 1 review

Regimens of vitamin D supplementation for women during pregnancy 2019 · Cochrane Headline outcomes only
RR 0.54 [0.34, 0.86]
5 studies · 1846 participants
Moderate

A dose of vitamin D 601 IU or higher vs 600 IU or lower alone or with other nutrients

Preterm birth · women during pregnancy

A dose of vitamin D 601 IU or higher showed no clear difference in preterm birth compared with 600 IU or lower alone or with other nutrients (low certainty).

1 finding from 1 review

Regimens of vitamin D supplementation for women during pregnancy 2019 · Cochrane Headline outcomes only
RR 1.25 [0.92, 1.69]
4 studies · 2294 participants
Low

A dose of vitamin D 601 IU or higher vs 600 IU or lower alone or with other nutrients

Low birthweight · women during pregnancy

It is very uncertain whether A dose of vitamin D 601 IU or higher changes low birthweight compared with 600 IU or lower alone or with other nutrients (very low certainty).

1 finding from 1 review

Regimens of vitamin D supplementation for women during pregnancy 2019 · Cochrane Headline outcomes only
RR 0.9 [0.66, 1.24]
4 studies · 1550 participants
Very low