Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

901 questions · 1,073 findings · 138 reviews

No studies found 166 · 15.5%GRADE not reported 310 · 28.9%Very low 213 · 19.9%Low 227 · 21.2%Moderate 132 · 12.3%High 25 · 2.3%

Higher vs lower omega‐6: additional key outcomes

MACCEs Study duration range 24‐96 months Omega‐6 dose range 2.8%‐12.0% E · adults with or without existing CVD

It is very uncertain whether higher changes MACCEs Study duration range 24‐96 months Omega‐6 dose range… compared with lower omega‐6: primary outcomes (very low certainty).

1 finding from 1 review

Higher vs lower omega‐6: additional key outcomes

Fatal or nonfatal stroke · adults with or without existing CVD

It is very uncertain whether higher changes stroke: fatal or non‐fatal Study duration range 24‐96 months Omega‐6… compared with lower omega‐6: primary outcomes (very low certainty).

1 finding from 1 review

Higher vs lower omega‐6: additional key outcomes

MI Study duration range 12‐96 months Omega‐6 dose range 2.8%‐24.5% E · adults with or without existing CVD

Higher showed no clear difference in MI Study duration range 12‐96 months Omega‐6 dose range 2.8%‐24.5% E compared with lower omega‐6: additional key outcomes (low certainty).

1 finding from 1 review