Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

901 questions · 1,073 findings · 138 reviews

No studies found 166 · 15.5%GRADE not reported 310 · 28.9%Very low 213 · 19.9%Low 227 · 21.2%Moderate 132 · 12.3%High 25 · 2.3%

High‐intensity vs low‐intensity exercise programmes

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · patients with patellofemoral pain syndrome (untreated PFPS of over 2 months in duration)

It is very uncertain whether high‐intensity changes usual pain (short‐term) VAS (0 to 10; higher scores mean worse pain) compared with low‐intensity exercise programmes (very low certainty).

2 findings from 1 review

High‐intensity vs low‐intensity exercise programmes

Functional ability · patients with patellofemoral pain syndrome (untreated PFPS of over 2 months in duration)

It is very uncertain whether high‐intensity changes functional ability (short‐term) FIQ modified (0 to 16; higher scores… compared with low‐intensity exercise programmes (very low certainty).

2 findings from 1 review

Higher vs lower omega‐6: additional key outcomes

All‐cause mortality Study duration range 12‐96 months Omega‐6 dose range 1.5%‐24.5% E · adults with or without existing CVD

Higher showed no clear difference in all‐cause mortality Study duration range 12‐96 months Omega‐6 dose… compared with lower omega‐6: primary outcomes (low certainty).

1 finding from 1 review

Higher vs lower omega‐6: additional key outcomes

Cardiovascular mortality · adults with or without existing CVD

It is very uncertain whether higher changes cardiovascular mortality Study duration range 24‐96 months Omega‐6… compared with lower omega‐6: primary outcomes (very low certainty).

1 finding from 1 review