Exacerbations · Adults with acute asthma
It is very uncertain whether adults: higher dose/longer course changes new exacerbation in compared with lower dose/shorter course (very low certainty).
2 findings from 1 review
FEV1 % predicted · Adults with acute asthma
1 finding from 1 review
All adverse events · Adults with acute asthma
It is very uncertain whether adults: higher dose/longer course changes all adverse events compared with lower dose/shorter course (very low certainty).
1 finding from 1 review
Adverse effects (loose stools, diarrhoea) · Infants (primary teeth; baseline about 9 to 15 months)
1 finding from 1 review
Adverse effects were not reported in a usable format, but the reported rates of loose stools and diarrhoea were very similar between groups. There were no serious adverse effects during the study. Milgrom 2009.
1 study · 94 participants
GRADE not reported
Caries in primary teeth (mean number of decayed primary teeth) · Infants (primary teeth; baseline about 9 to 15 months)
1 finding from 1 review
Mental state: 2. Not improved (BPRS, < 30% decrease in BPRS score) · patients with acute schizophrenia and similar serious mental illnesses
ZUCLOPENTHIXOL ACETATE (HIGH DOSE) showed no clear difference in mental state: 2. Not improved (BPRS, < 30% decrease in BPRS score) compared with ZUCLOPENTHIXOL ACETATE (LOW DOSE) (low certainty).
1 finding from 1 review
Adverse effects/events ‐ extrapyramidal symptoms ‐ medium term Number of instances of extrapyramidal symptoms · patients with acute schizophrenia and similar serious mental illnesses
ZUCLOPENTHIXOL ACETATE (HIGH DOSE) showed no clear difference in adverse effects: 1. Extrapyramidal side effects (TESS) compared with ZUCLOPENTHIXOL ACETATE (LOW DOSE) (low certainty).
1 finding from 1 review
Sedation/tranquillisation: Not sedated ‐ at four hours · patients with acute schizophrenia and similar serious mental illnesses
1 finding from 1 review
Global state: 1. Requiring supplementary medication ‐ antipsychotics · patients with acute schizophrenia and similar serious mental illnesses
1 finding from 1 review
Global state: 2. Requiring 3 or more injections ‐ over 7 days · patients with acute schizophrenia and similar serious mental illnesses
1 finding from 1 review
Mental state: 1. Not markedly improved (BPRS, < 60% decrease in BPRS score) · patients with acute schizophrenia and similar serious mental illnesses
ZUCLOPENTHIXOL ACETATE (HIGH DOSE) showed no clear difference in mental state: 1. Not markedly improved (BPRS, < 60% decrease in BPRS… compared with ZUCLOPENTHIXOL ACETATE (LOW DOSE) (low certainty).
1 finding from 1 review
IU vs 100 IU · women undergoing IVF/ICSI who are anticipated to have a hyper‐response to stimulation based on at least one ORT measure
Anticipated high responders: higher showed no clear difference in IU vs 100 IU compared with lower dose of FSH (low certainty).
1 finding from 1 review
Wound infection · Adults with mandibular third molars requiring removal
It is very uncertain whether mechanical (high-volume) irrigation changes wound infection compared with manual (low-volume) irrigation (very low certainty).
1 finding from 1 review
Presence of dry socket · Adults with mandibular third molars requiring removal
It is very uncertain whether mechanical (high-volume) irrigation changes alveolar osteitis compared with manual (low-volume) irrigation (very low certainty).
1 finding from 1 review
Re‐admission during · children with acute asthma
1 finding from 1 review
Asthma symptoms · children with acute asthma
Children: higher dose/longer course showed no clear difference in asthma symptoms Symptom free by 7 days compared with lower dose/shorter course (moderate certainty).
1 finding from 1 review
Serious adverse events · children with acute asthma
1 finding from 1 review
Exacerbations · children with acute asthma
Children: higher dose/longer course showed no clear difference in new exacerbation during compared with lower dose/shorter course (low certainty).
2 findings from 1 review
FEV1 % predicted · children with acute asthma
1 finding from 1 review
All adverse events · children with acute asthma
Children: higher dose/longer course showed no clear difference in all adverse events compared with lower dose/shorter course (moderate certainty).
1 finding from 1 review