Second cancers at 4 ‐ 9‐year median · women with early poor prognosis breast cancer
High‐dose chemotherapy showed no clear difference in second cancers at 4 ‐ 9‐year median compared with chemotherapy without bone marrow transplant or stem cell rescue (high certainty).
1 finding from 1 review
Restoration survival · Children with decayed primary molar teeth
Multi-surface ART/HVGIC restorations had lower reported survival (49% at 3 years) than single-surface restorations (ungraded).
1 finding from 1 review
Survival rate (%) 49
9 studies
GRADE not reported
Restoration failure · Children (2-9 years) with caries in posterior primary teeth
Multi-surface ART restorations had a high reported mean annual failure rate (17%; ungraded).
1 finding from 1 review
Restoration failure · Children (2-9 years) with caries in posterior primary teeth
Single-surface ART restorations had a low reported mean annual failure rate (about 5%; ungraded).
1 finding from 1 review
Restoration survival · Children with decayed primary molar teeth
Single-surface ART/HVGIC restorations had high reported survival (86% at 3 years), significantly higher than multi-surface restorations (ungraded).
1 finding from 1 review
Survival rate (%) 86
9 studies
GRADE not reported
Treatment failure rate · patients with osteoarthritis of the knee
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Pain · patients with osteoarthritis of the knee
1 finding from 1 review
Function · patients with osteoarthritis of the knee
1 finding from 1 review
Health‐related quality of life measures · patients with osteoarthritis of the knee
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Serious adverse events · patients with osteoarthritis of the knee
Other types of high tibial osteotomy (aHTO) showed no clear difference in serious adverse events compared with closing wedge high tibial osteotomy (CW‐HTO) (low certainty).
1 finding from 1 review
All‐cause mortality · patients with osteoarthritis of the knee
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Reoperation rate · patients with osteoarthritis of the knee
Other types of high tibial osteotomy (aHTO) may leads to higher reoperation rate compared with closing wedge high tibial osteotomy (CW‐HTO) (low certainty).
1 finding from 1 review
Caries experience (mean DMFT) · 12-year-old children across European countries (national/regional epidemiological surveys, 2011-2022)
Mean DMFT was higher in high-HDI (3.41) than very-high-HDI (1.73) countries (ANOVA p<.01); descriptive country-level means only, not meta-analyzed or GRADE-rated.
2 findings from 1 review
QoL · people with CAH
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Androgen normalisation · people with CAH
1 finding from 1 review
no estimate extracted
15 participants
Very low
Prevention of adrenal crisis · people with CAH
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Presence of osteopenia · people with CAH
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Presence of testicular or ovarian adrenal rest tumours · people with CAH
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Subfertility · people with CAH
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Final adult height · people with CAH
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found