Findings

What do systematic reviews say?

5 questions · 5 findings · 1 reviews · Acute Respiratory Infections

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 2 · 40%Moderate 3 · 60%High 0 · 0%

Gastrointestinal adverse events in people taking macrolide antibiotics vs placebo

Gastrointestinal disorders not otherwise specified · any indication

Gastrointestinal adverse events in people taking macrolide antibiotics probably leads to higher gastrointestinal disorders not otherwise specified compared with placebo (moderate certainty).

1 finding from 1 review

Adverse events in people taking macrolide antibiotics versus placebo for any indication 2019 · Cochrane Headline outcomes only
OR 2.16 [1.56, 3]
23 studies · 3295 participants
Moderate

Gastrointestinal adverse events in people taking macrolide antibiotics vs placebo

Abdominal pain · any indication

Gastrointestinal adverse events in people taking macrolide antibiotics may leads to higher abdominal pain compared with placebo (low certainty).

1 finding from 1 review

Adverse events in people taking macrolide antibiotics versus placebo for any indication 2019 · Cochrane Headline outcomes only
OR 1.66 [1.22, 2.26]
23 studies · 7776 participants
Low

Gastrointestinal adverse events in people taking macrolide antibiotics vs placebo

Diarrhoea · any indication

Gastrointestinal adverse events in people taking macrolide antibiotics may leads to higher diarrhoea compared with placebo (low certainty).

1 finding from 1 review

Adverse events in people taking macrolide antibiotics versus placebo for any indication 2019 · Cochrane Headline outcomes only
OR 1.7 [1.34, 2.16]
37 studies · 23754 participants
Low

Gastrointestinal adverse events in people taking macrolide antibiotics vs placebo

Nausea · any indication

Gastrointestinal adverse events in people taking macrolide antibiotics probably leads to higher nausea compared with placebo (moderate certainty).

1 finding from 1 review

Adverse events in people taking macrolide antibiotics versus placebo for any indication 2019 · Cochrane Headline outcomes only
OR 1.61 [1.37, 1.9]
28 studies · 14983 participants
Moderate

Gastrointestinal adverse events in people taking macrolide antibiotics vs placebo

Vomiting · any indication

Gastrointestinal adverse events in people taking macrolide antibiotics probably leads to higher vomiting compared with placebo (moderate certainty).

1 finding from 1 review

Adverse events in people taking macrolide antibiotics versus placebo for any indication 2019 · Cochrane Headline outcomes only
OR 1.27 [1.04, 1.56]
15 studies · 5328 participants
Moderate