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What do systematic reviews say?

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Evidence found and GRADE certainty

3 questions · 5 findings · 1 reviews · Drugs and Alcohol

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 4 · 80%Moderate 1 · 20%High 0 · 0%

Full opioid agonists vs different full opioid agonists or partial opioid agonists (methadone versus buprenorphine)

Illicit opioid use · pharmaceutical opioid dependent people

Full opioid agonists showed no clear difference in illicit opioid use compared with different full opioid agonists or partial opioid agonists (methadone… (moderate certainty).

3 findings from 1 review

Full opioid agonists vs different full opioid agonists or partial opioid agonists (methadone versus buprenorphine)

Retention [ · pharmaceutical opioid dependent people

Full opioid agonists may leads to higher retention compared with different full opioid agonists or partial opioid agonists (methadone… (low certainty).

1 finding from 1 review

Full opioid agonists vs different full opioid agonists or partial opioid agonists (methadone versus buprenorphine)

Adverse effects · pharmaceutical opioid dependent people

Full opioid agonists showed no clear difference in adverse effects compared with different full opioid agonists or partial opioid agonists (methadone… (low certainty).

1 finding from 1 review