Number of visits to the dentist for repair of sealant or fluoride varnish application · Children and adolescents (general population, aged under 20 years)
The review found no eligible studies for this question.
1 finding from 1 review
Time taken to apply pit and fissure sealant or fluoride varnish · Children and adolescents (general population, aged under 20 years)
1 finding from 1 review
Coronal carious lesions prevention · Children with coronal carious lesions (primary dentition)
One review reported a 54% prevented fraction for fluoride varnish versus placebo for preventing coronal caries in primary teeth (one study; ungraded; comparator intervention, not SDF).
1 finding from 1 review
Prevented Fraction 54
1 study
GRADE not reported
Unacceptability of treatment (drop-outs / leaving study early) · Children and adolescents aged 16 years or less
Fluoride varnish showed no clear difference in unacceptability of treatment (drop-outs) compared with fluoride toothpaste; GRADE not reported.
1 finding from 1 review
RR 1.28 [0.37, 4.41]
1 study
GRADE not reported
Proportion of children developing new caries (deciduous) · Children and adolescents aged 16 years or less
1 finding from 1 review
Caries increment in permanent teeth · Children and adolescents aged 16 years or less
1 finding from 1 review
Caries increment in permanent teeth · Children and adolescents aged 16 years or less
1 finding from 1 review
Caries increment (dfs), deciduous teeth · Children and adolescents aged 16 years or less
1 finding from 1 review
Unacceptability of treatment (drop-outs / leaving study early) · Children and adolescents aged 16 years or less
Fluoride varnish showed no clear difference in unacceptability of treatment (drop-outs) compared with fluoride mouthrinse; GRADE not reported.
1 finding from 1 review
RR 1.19 [0.86, 1.65]
2 studies
GRADE not reported
Contribution of dental care products to total daily fluoride intake (TDFI) · Humans using fluoride-containing dental care products; 28 included studies, mostly young children, only two studies in adults (aged…
Fluoride-containing dental care products (mainly toothpaste) contributed on average 38% (SD 27%) of total daily fluoride intake, regardless of tap-water fluoride level or age (ungraded; descriptive synthesis, no meta-analysis).
1 finding from 1 review
Proportion of children developing new caries (deciduous) · Children and adolescents aged 16 years or less
Fluoride varnish showed no clear difference in proportion of children developing one or more new caries… compared with placebo or no treatment; GRADE not reported.
1 finding from 1 review
Adverse effects / specific side effects (oral allergic reactions, mucosal irritation, adverse symptoms such as nausea, gagging, vomiting) · Children and adolescents aged 16 years or less
1 finding from 1 review
Caries increment in primary/deciduous teeth: decayed, (extraction indicated/missing) and filled teeth d(e/m)ft (prevented fraction) · Children and adolescents aged 16 years or less
1 finding from 1 review
Proportion of children developing new caries (permanent) · Children and adolescents aged 16 years or less
Fluoride varnish showed no clear difference in proportion of children developing one or more new caries (permanent… compared with placebo or no treatment; GRADE not reported.
1 finding from 1 review
Caries increment on permanent whole teeth (D(M)FT), prevented fraction · Children and adolescents aged 16 years or less
1 finding from 1 review
PF 0.44 [0.11, 0.76]
5 studies
GRADE not reported
Caries increment on permanent tooth surfaces (D(M)FS), prevented fraction · Children and adolescents aged 16 years or less
1 finding from 1 review
Caries increment on primary (deciduous) tooth surfaces (d(e/m)fs), prevented fraction · Children and adolescents aged 16 years or less
1 finding from 1 review
Fluorosis (percentage prevalence in permanent teeth) · Children exposed to topical fluoride when under 6 years old; fluorosis assessed in permanent teeth at 6 to 18 years
Fluoride varnish applied before 4 years of age may leads to higher fluorosis (percentage prevalence in permanent teeth) compared with no fluoride varnish application (low certainty).
1 finding from 1 review
Remineralization / reduction in lesion severity (change in QLF, laser fluorescence, or lesion area) · Patients with white spot lesions / early caries lesions (WSLs/ECLs), including orthodontic and non-orthodontic lesions, active caries…
P11-4 plus fluoride varnish was significantly better than fluoride varnish alone (SMD -0.71, 95% CI -1.13 to -0.29); certainty of evidence not assessed (no GRADE).
1 finding from 1 review
Progression of dentinal carious lesions into enamel or dentine · Children and adolescents (general population, aged under 20 years)
The review found no eligible studies for this question.
1 finding from 1 review