Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

23 questions · 23 findings · 3 reviews

No studies found 1 · 4.3%GRADE not reported 0 · 0%Very low 9 · 39.1%Low 8 · 34.8%Moderate 5 · 21.7%High 0 · 0%

Extended vs short duration antibiotics

Surgical site infections: liver transplant recipients Time frame: 30 days · solid organ transplant recipients

It is very uncertain whether extended changes surgical site infections: liver transplant recipients Time frame: 30… compared with short duration antibiotics (very low certainty).

1 finding from 1 review

Extended vs short duration antibiotics

Graft loss including death · solid organ transplant recipients

It is very uncertain whether extended changes graft loss (including death with functioning graft) Time frame: 30… compared with short duration antibiotics (very low certainty).

1 finding from 1 review

Extended vs short duration antibiotics

Other infection: septicaemia Time frame: 2 to 6 weeks · solid organ transplant recipients

It is very uncertain whether extended changes other infection: septicaemia Time frame: 30 days compared with short duration antibiotics (very low certainty).

1 finding from 1 review

Extended vs short duration antibiotics

Other infection: pneumonia Time frame: 30 days · solid organ transplant recipients

It is very uncertain whether extended changes other infection: pneumonia Time frame: 30 days compared with short duration antibiotics (very low certainty).

1 finding from 1 review

Extended vs short duration antibiotics

Surgical site infections: kidney transplant recipients Time frame: 30 days · solid organ transplant recipients

It is very uncertain whether extended changes surgical site infections: kidney transplant recipients Time frame:… compared with short duration antibiotics (very low certainty).

1 finding from 1 review

An extended ZDV/3TC/LPV/r regimen administered to mothers vs Short‐Course AZT (intrapartum AZT/3TC/sd‐NVP)

HIV transmission at 6 months among those whose diagnostic testing was negative at 6 weeks after birth · HIV‐infected mothers and their breastfeeding infants

An extended ZDV/3TC/LPV/r regimen administered to mothers showed no clear difference in HIV transmission at 6 months among those whose diagnostic testing… compared with short course ZDV (intrapartum ZDV/3TC/sdNVP) (low certainty).

1 finding from 1 review

An extended ZDV/3TC/LPV/r regimen administered to mothers vs Short‐Course AZT (intrapartum AZT/3TC/sd‐NVP)

HIV transmission at 12 months among those whose diagnostic testing was negative at 6 weeks after birth · HIV‐infected mothers and their breastfeeding infants

An extended ZDV/3TC/LPV/r regimen administered to mothers may leads to lower HIV transmission at 12 months among those whose diagnostic testing… compared with short course ZDV (intrapartum ZDV/3TC/sdNVP) (low certainty).

1 finding from 1 review

An extended ZDV/3TC/LPV/r regimen administered to mothers vs Short‐Course AZT (intrapartum AZT/3TC/sd‐NVP)

Infant Mortality at 6 Months · HIV‐infected mothers and their breastfeeding infants

An extended ZDV/3TC/LPV/r regimen administered to mothers showed no clear difference in infant Mortality at 6 months compared with short course ZDV (intrapartum ZDV/3TC/sdNVP) (low certainty).

1 finding from 1 review

An extended ZDV/3TC/LPV/r regimen administered to mothers vs Short‐Course AZT (intrapartum AZT/3TC/sd‐NVP)

Infant Mortality at 12 months · HIV‐infected mothers and their breastfeeding infants

An extended ZDV/3TC/LPV/r regimen administered to mothers showed no clear difference in infant Mortality at 12 months compared with short course ZDV (intrapartum ZDV/3TC/sdNVP) (low certainty).

1 finding from 1 review