Findings

What do systematic reviews say?

186 questions · 195 findings · 13 reviews

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No studies found 63 · 32.3%GRADE not reported 3 · 1.5%Very low 46 · 23.6%Low 51 · 26.2%Moderate 17 · 8.7%High 15 · 7.7%

Manual therapy and exercise vs placebo

Function · rotator cuff disease

1 finding from 1 review

Manual therapy and exercise for rotator cuff disease 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 120 participants
High

Manual therapy and exercise vs placebo

Pain on motion · rotator cuff disease

1 finding from 1 review

Manual therapy and exercise for rotator cuff disease 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 120 participants
High

Manual therapy and exercise vs placebo

Global assessment of treatment success · rotator cuff disease

Manual therapy and exercise showed no clear difference in global assessment of treatment success compared with placebo (high certainty).

1 finding from 1 review

Manual therapy and exercise for rotator cuff disease 2016 · Cochrane Headline outcomes only
RR 1.39 [0.94, 2.03]
1 study · 112 participants
High

Manual therapy and exercise vs placebo

Quality of life · rotator cuff disease

1 finding from 1 review

Manual therapy and exercise for rotator cuff disease 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 120 participants
High

Manual therapy and exercise vs placebo

Adverse events · rotator cuff disease

Manual therapy and exercise leads to higher adverse events compared with placebo (high certainty).

1 finding from 1 review

Manual therapy and exercise for rotator cuff disease 2016 · Cochrane Headline outcomes only
RR 3.77 [1.49, 9.54]
1 study · 116 participants
High

Manual therapy and exercise vs glucocorticoid injection

Overall pain · rotator cuff disease

1 finding from 1 review

Manual therapy and exercise for rotator cuff disease 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 88 participants
Low

Manual therapy and exercise vs glucocorticoid injection

Function · rotator cuff disease

1 finding from 1 review

Manual therapy and exercise for rotator cuff disease 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 88 participants
Low

Manual therapy and exercise vs glucocorticoid injection

Pain on motion · rotator cuff disease

The review found no eligible studies for this question.

1 finding from 1 review

Manual therapy and exercise for rotator cuff disease 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings table ‐ Adjunctive therapies in addition to land‐based exercise therapy vs land‐based exercise therapy

Quality of life ‐ total · Patients with osteoarthritis of the knee or hip

1 finding from 1 review

Adjunctive therapies in addition to land‐based exercise therapy for osteoarthritis of the hip or knee 2022 · Cochrane Headline outcomes only
no estimate extracted
10 studies · 1483 participants
Very low

Summary of findings table ‐ Adjunctive therapies in addition to land‐based exercise therapy vs land‐based exercise therapy

Participant‐reported global assessment‐ total · Patients with osteoarthritis of the knee or hip

Summary of findings table ‐ Adjunctive therapies in addition to… probably leads to higher participant‐reported global assessment‐ total compared with land‐based exercise therapy (moderate certainty).

1 finding from 1 review

Adjunctive therapies in addition to land‐based exercise therapy for osteoarthritis of the hip or knee 2022 · Cochrane Headline outcomes only
RR 1.37 [1.15, 1.62]
5 studies · 840 participants
Moderate

Summary of findings table ‐ Adjunctive therapies in addition to land‐based exercise therapy vs land‐based exercise therapy

Radiographic joint changes · Patients with osteoarthritis of the knee or hip

1 finding from 1 review

Adjunctive therapies in addition to land‐based exercise therapy for osteoarthritis of the hip or knee 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 156 participants
Low

Summary of findings table ‐ Adjunctive therapies in addition to land‐based exercise therapy vs land‐based exercise therapy

Adverse events · Patients with osteoarthritis of the knee or hip

Summary of findings table ‐ Adjunctive therapies in addition to… showed no clear difference in adverse events compared with land‐based exercise therapy (low certainty).

1 finding from 1 review

Adjunctive therapies in addition to land‐based exercise therapy for osteoarthritis of the hip or knee 2022 · Cochrane Headline outcomes only
RR 1.33 [0.78, 2.27]
8 studies · 1542 participants
Low

Summary of findings table ‐ Adjunctive therapies in addition to land‐based exercise therapy vs land‐based exercise therapy

Withdrawals due to adverse events · Patients with osteoarthritis of the knee or hip

The review found no eligible studies for this question.

1 finding from 1 review

Adjunctive therapies in addition to land‐based exercise therapy for osteoarthritis of the hip or knee 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings table ‐ Adjunctive therapies in addition to land‐based exercise therapy vs land‐based exercise therapy

Pain ‐ total · Patients with osteoarthritis of the knee or hip

1 finding from 1 review

Adjunctive therapies in addition to land‐based exercise therapy for osteoarthritis of the hip or knee 2022 · Cochrane Headline outcomes only
no estimate extracted
41 studies · 3322 participants
Low

Summary of findings table ‐ Adjunctive therapies in addition to land‐based exercise therapy vs land‐based exercise therapy

Physical function · Patients with osteoarthritis of the knee or hip

1 finding from 1 review

Adjunctive therapies in addition to land‐based exercise therapy for osteoarthritis of the hip or knee 2022 · Cochrane Headline outcomes only
no estimate extracted
41 studies · 3323 participants
Very low

Exercise therapy plus antidepressants vs antidepressants alone

FatigueMeasured at end of treatment, 26 weeks · men and women aged over 18 years with chronic fatigue syndrome

1 finding from 1 review

Exercise therapy for chronic fatigue syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 43 participants
Very low

Exercise therapy plus antidepressants vs antidepressants alone

Fatigue · men and women aged over 18 years with chronic fatigue syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Exercise therapy for chronic fatigue syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Exercise therapy plus antidepressants vs antidepressants alone

Participants with serious adverse reactions · men and women aged over 18 years with chronic fatigue syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Exercise therapy for chronic fatigue syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Exercise therapy plus antidepressants vs antidepressants alone

Pain End of treatment and long term · men and women aged over 18 years with chronic fatigue syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Exercise therapy for chronic fatigue syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Exercise therapy plus antidepressants vs antidepressants alone

Physical functioning End of treatment and long term · men and women aged over 18 years with chronic fatigue syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Exercise therapy for chronic fatigue syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found