Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

251 questions · 260 findings · 20 reviews · Headline outcomes only

No studies found 75 · 28.8%GRADE not reported 3 · 1.2%Very low 65 · 25%Low 75 · 28.8%Moderate 27 · 10.4%High 15 · 5.8%

Exercise therapy vs adaptive pacing therapy

Participants with serious adverse reactions · men and women aged over 18 years with chronic fatigue syndrome

It is very uncertain whether exercise therapy changes participants with serious adverse reactions Measured after 52 weeks… compared with adaptive pacing therapy (very low certainty).

1 finding from 1 review