Findings

What do systematic reviews say?

205 questions · 208 findings · 15 reviews · Musculoskeletal

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No studies found 42 · 20.2%GRADE not reported 14 · 6.7%Very low 45 · 21.6%Low 60 · 28.8%Moderate 31 · 14.9%High 16 · 7.7%

Exercise vs no exercise

Adverse events due to exercise · rheumatoid arthritis of the hand

1 finding from 1 review

Exercise for rheumatoid arthritis of the hand 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 490 participants
Moderate

Exercise vs no exercise

Hand function ‐ short term (less than 3 months) Grip function test scale of 0 to 80 points (higher score indicates better grip function) · rheumatoid arthritis of the hand

1 finding from 1 review

Exercise for rheumatoid arthritis of the hand 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 24 participants
Very low

Exercise vs no exercise

Hand impairment ‐ power grip strength of both hands (kg) ‐ long term (12 months and beyond) · rheumatoid arthritis of the hand

1 finding from 1 review

Exercise for rheumatoid arthritis of the hand 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 355 participants
High

Exercise vs no exercise

Hand impairment ‐ pinch grip strength (kg) ‐ left hand ‐ short term (less than 3 months) · rheumatoid arthritis of the hand

1 finding from 1 review

Exercise for rheumatoid arthritis of the hand 2018 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 120 participants
Very low

Exercise vs no exercise

Hand impairment ‐ pinch grip strength (kg) ‐ right hand ‐ short term (less than 3 months) · rheumatoid arthritis of the hand

1 finding from 1 review

Exercise for rheumatoid arthritis of the hand 2018 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 120 participants
Very low

Exercise vs no exercise

Hand impairment ‐ pinch grip strength of both hands (kg) ‐ medium term (3 to 11 months) · rheumatoid arthritis of the hand

1 finding from 1 review

Exercise for rheumatoid arthritis of the hand 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 396 participants
High

Exercise vs no exercise

Hand impairment ‐ pinch grip strength of both hands (kg) ‐ long term (12 months and beyond) · rheumatoid arthritis of the hand

1 finding from 1 review

Exercise for rheumatoid arthritis of the hand 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 351 participants
High

Exercise vs no exercise

ACR50 response · rheumatoid arthritis of the hand

1 finding from 1 review

Exercise for rheumatoid arthritis of the hand 2018 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Exercise vs no exercise

Adherence · rheumatoid arthritis of the hand

Exercise probably leads to higher participant adherence ‐ medium term (3 to 11 months) compared with no exercise (moderate certainty).

2 findings from 1 review

Exercise for rheumatoid arthritis of the hand 2018 · Cochrane Headline outcomes only
RR 1.31 [1.15, 1.48]
1 study · 438 participants
Moderate
Exercise for rheumatoid arthritis of the hand 2018 · Cochrane Headline outcomes only
RR 1.09 [0.93, 1.28]
1 study · 422 participants
Moderate

Hand function ‐ long term (12 months and beyond) Overall hand function subscale of the Michigan Hand Questionnaire, 0 to 100 (higher scores mean better hand function) · rheumatoid arthritis of the hand

2 findings from 1 review

Exercise for rheumatoid arthritis of the hand 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 449 participants
Moderate
Exercise for rheumatoid arthritis of the hand 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 438 participants
Moderate

Exercise vs no exercise

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · rheumatoid arthritis of the hand

2 findings from 1 review

Exercise for rheumatoid arthritis of the hand 2018 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 124 participants
Very low
Exercise for rheumatoid arthritis of the hand 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 445 participants
Moderate

Exercise vs no exercise

Pain ‐ long term (12 months and beyond) Pain subscale of Michigan Hand Outcomes Questionnaire (0 to 100 points, higher score means more pain) · rheumatoid arthritis of the hand

1 finding from 1 review

Exercise for rheumatoid arthritis of the hand 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 437 participants
Moderate

Exercise vs no exercise

Hand impairment ‐ power grip strength (kg) ‐ left hand ‐ short term (less than 3 months) · rheumatoid arthritis of the hand

1 finding from 1 review

Exercise for rheumatoid arthritis of the hand 2018 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 141 participants
Very low

Exercise vs no exercise

Hand impairment ‐ power grip strength (kg) ‐ right hand ‐ short term (less than 3 months) · rheumatoid arthritis of the hand

1 finding from 1 review

Exercise for rheumatoid arthritis of the hand 2018 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 141 participants
Very low

Exercise vs no exercise

Hand impairment ‐ power grip strength of both hands (kg) ‐ medium term (3 to 11 months) · rheumatoid arthritis of the hand

1 finding from 1 review

Exercise for rheumatoid arthritis of the hand 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 400 participants
High

Exercise vs usual care

Adverse effects associated with exercises Exercise programme duration: range 3 to 24 weeks · adults with ankylosing spondylitis

It is very uncertain whether exercise programmes changes adverse effects associated with exercises Exercise programme… compared with usual care (very low certainty).

1 finding from 1 review

Exercise programmes for ankylosing spondylitis 2019 · Cochrane Headline outcomes only
Peto OR 6.25 [0.1, 320.4]
2 studies · 110 participants
Very low

Exercise vs usual care

Adverse events Exercise programme duration: range 3 to 24 weeks · adults with ankylosing spondylitis

1 finding from 1 review

Exercise programmes for ankylosing spondylitis 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Exercise vs no intervention

Adverse effects associated with exercises Exercise programme duration: range 3 to 24 weeks · adults with ankylosing spondylitis

It is very uncertain whether exercise programmes changes adverse effects associated with exercises Exercise programme… compared with no intervention (very low certainty).

1 finding from 1 review

Exercise programmes for ankylosing spondylitis 2019 · Cochrane Headline outcomes only
Peto OR 6.25 [0.1, 320.4]
2 studies · 110 participants
Very low

Exercise vs no intervention

Withdrawals due to adverse events · adults with ankylosing spondylitis

Exercise programmes showed no clear difference in withdrawals because of adverse events Exercise programme duration:… compared with no intervention (low certainty).

1 finding from 1 review

Exercise programmes for ankylosing spondylitis 2019 · Cochrane Headline outcomes only
Peto OR 1.08 [0.74, 1.57]
8 studies · 1343 participants
Low

Hand exercise vs no exercise

Hand pain Self‐report questionnaires Scale from 0 to 10 (0 represents no pain) · patients with hand osteoarthritis

1 finding from 1 review

Exercise for hand osteoarthritis 2017 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 381 participants
Low