Findings

What do systematic reviews say?

6 questions · 6 findings · 2 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 16.7%Moderate 5 · 83.3%High 0 · 0%

Endovascular therapy plus conventional medical treatment vs conventional medical treatment alone

Death or stroke · people with symptomatic intracranial artery stenosis

Endovascular therapy plus conventional medical treatment probably leads to higher death or stroke compared with conventional medical treatment alone (moderate certainty).

1 finding from 1 review

Endovascular therapy versus medical treatment for symptomatic intracranial artery stenosis 2023 · Cochrane Headline outcomes only
RR 2.93 [1.81, 4.75]
4 studies · 989 participants
Moderate

Endovascular therapy plus conventional medical treatment vs conventional medical treatment alone

Long‐term ipsilateral stroke · people with symptomatic intracranial artery stenosis

Endovascular therapy plus conventional medical treatment probably leads to higher ipsilateral stroke compared with conventional medical treatment alone (moderate certainty).

1 finding from 1 review

Endovascular therapy versus medical treatment for symptomatic intracranial artery stenosis 2023 · Cochrane Headline outcomes only
RR 3.26 [1.94, 5.48]
4 studies · 989 participants
Moderate

Endovascular therapy plus conventional medical treatment vs medical treatment

Stroke or TIAMedian · people with vertebral artery stenosis

Endovascular treat ment plus medical treatment showed no clear difference in stroke or TIAMedian compared with medical treatment alone (moderate certainty).

1 finding from 1 review

Percutaneous transluminal angioplasty and stenting for vertebral artery stenosis 2022 · Cochrane Headline outcomes only
RR 0.65 [0.39, 1.06]
2 studies · 234 participants
Moderate

Endovascular therapy plus conventional medical treatment vs medical treatment

Death or stroke · people with vertebral artery stenosis

Endovascular treat ment plus medical treatment showed no clear difference in 30‐day post‐randomisation death/stroke compared with medical treatment alone (low certainty).

1 finding from 1 review

Percutaneous transluminal angioplasty and stenting for vertebral artery stenosis 2022 · Cochrane Headline outcomes only
RR 2.33 [0.77, 7.07]
3 studies · 349 participants
Low

Endovascular therapy plus conventional medical treatment vs medical treatment

Stroke (ischaemic or haemorrhagic)Median · people with vertebral artery stenosis

Endovascular treat ment plus medical treatment showed no clear difference in stroke (ischaemic or haemorrhagic)Median compared with medical treatment alone (moderate certainty).

1 finding from 1 review

Percutaneous transluminal angioplasty and stenting for vertebral artery stenosis 2022 · Cochrane Headline outcomes only
RR 0.77 [0.44, 1.32]
3 studies · 349 participants
Moderate

Endovascular therapy plus conventional medical treatment vs medical treatment

Fatal/non‐fatal stroke in the territory of the treated vertebral artery stenosis(assessed after 30 days post‐randomisation to completion of · people with vertebral artery stenosis

Endovascular treat ment plus medical treatment showed no clear difference in fatal/non‐fatal stroke in the territory of the treated vertebral… compared with medical treatment alone (moderate certainty).

1 finding from 1 review

Percutaneous transluminal angioplasty and stenting for vertebral artery stenosis 2022 · Cochrane Headline outcomes only
RR 0.51 [0.26, 1.01]
3 studies · 349 participants
Moderate