Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

720 questions · 804 findings · 103 reviews

No studies found 207 · 25.7%GRADE not reported 161 · 20%Very low 192 · 23.9%Low 160 · 19.9%Moderate 78 · 9.7%High 6 · 0.7%

Follow‐up integrating additional patient symptom education or monitoring, or survivorship care plans vs usual care

Overall survival · adult cancer survivors from the following cancer sites: breast, colorectal, endometrial, ovarian and prostate cancer

The review found no eligible studies for this question.

1 finding from 1 review

Follow‐up integrating additional patient symptom education or monitoring, or survivorship care plans vs usual care

Time to detection of recurrence · adult cancer survivors from the following cancer sites: breast, colorectal, endometrial, ovarian and prostate cancer

The review found no eligible studies for this question.

1 finding from 1 review

Oral health education only (verbal, written, or audio-visual education) delivered by non-dental health workers vs control (no intervention/usual care/isotonic exercise)

Caries experience · Children (mean age newborn to ~5.2 years) and their parents/carers

Oral-health-education-only interventions showed at most a marginal effect on tooth-level caries (dmft SMD -0.11, 95% CI -0.21 to -0.00; 2 studies; not GRADE-rated).

1 finding from 1 review

Oral health education only (verbal, written, or audio-visual education) delivered by non-dental health workers vs control (no intervention/usual care/isotonic exercise)

Caries experience at the surface level (dmfs/defs) · Children (mean age newborn to ~5.2 years) and their parents/carers

Oral-health-education-only interventions did not show a statistically significant effect on surface-level caries (dmfs SMD -0.20, 95% CI -0.43 to 0.03; 2 studies; not GRADE-rated).

1 finding from 1 review

Sociodemographic / socioeconomic factors (single-parent family, low parental education, family income, socioeconomic status) vs Absence of the factor / reference socioeconomic category

Caries increment in permanent teeth · School children and adolescents (6-18 years) followed from primary dentition (baseline examination before 72 months of age)

Evidence on the association between sociodemographic/socioeconomic factors and permanent-teeth caries is weak and inconsistent (3 studies; could not be pooled; not GRADE-rated).

1 finding from 1 review

Primary care physician alerting system and a patient‐directed intervention (education and reminder to see their primary care physician) vs usual care

Bone mineral density · General practitioners/family doctors involved in the management of patients with osteoporosis

Primary care physician alerting system and a patient‐directed… leads to higher bone Mineral Density 1 compared with standard care (high certainty).

1 finding from 1 review

Primary care physician alerting system and a patient‐directed intervention (education and reminder to see their primary care physician) vs usual care

Osteoporosis medication 2 · General practitioners/family doctors involved in the management of patients with osteoporosis

Primary care physician alerting system and a patient‐directed… leads to higher osteoporosis medication 2 compared with standard care (high certainty).

1 finding from 1 review

Perinatal death review and audit as part of an intervention package including an educational outreach visit and morbidity/mortality conferences vs no intervention

Perinatal mortality rate (overall) (at month 12–26) · births

Perinatal death review and audit as part of an intervention package… showed no clear difference in perinatal mortality rate (overall) (at month 12–26) compared with no intervention (low certainty).

1 finding from 1 review

Perinatal death review and audit as part of an intervention package including an educational outreach visit and morbidity/mortality conferences vs no intervention

Proportion of perinatal deaths related to suboptimal carec (at months 12–26) · births

It is very uncertain whether perinatal death review and audit as part of an intervention package… changes proportion of perinatal deaths related to suboptimal carec (at… compared with no intervention (very low certainty).

1 finding from 1 review

Perinatal death review and audit as part of an intervention package including an educational outreach visit and morbidity/mortality conferences vs no intervention

Mortality measured by mortality rates including failure‐to‐rescuerates (3a) Stillbirth · births

The review found no eligible studies for this question.

1 finding from 1 review

Perinatal death review and audit as part of an intervention package including an educational outreach visit and morbidity/mortality conferences vs no intervention

Proportion of perinatal morbidity cases related to suboptimal carec (at months 12–26) · births

Perinatal death review and audit as part of an intervention package… probably leads to lower proportion of perinatal morbidity cases related to suboptimal carec… compared with no intervention (moderate certainty).

1 finding from 1 review

Community and caregiver oral health education plus media campaign vs Pre-intervention baseline (and sites that discontinued the prevention program)

Reduction in prevalence of baby bottle tooth decay (BBTD) · Alaska Native and American Indian Head Start children

Community and caregiver oral health education was associated with a significant ~25% overall reduction in baby bottle tooth decay among Head Start children (certainty not graded).

1 finding from 1 review