Findings

What do systematic reviews say?

3 questions · 3 findings · 1 reviews · Gynaecological, Neuro-oncology and Orphan Cancer

Sort:Best matchNewest Highest certainty Download CSV

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 2 · 66.7%Low 1 · 33.3%Moderate 0 · 0%High 0 · 0%

Early discontinuation of antibiotic treatment vs treatment until neutropenia resolution

All‐cause mortality · febrile neutropenia

Early discontinuation of antibiotic treatment showed no clear difference in mortality compared with treatment until neutropenia resolution (low certainty).

1 finding from 1 review

Early discontinuation of antibiotics for febrile neutropenia versus continuation until neutropenia resolution in… 2019 · Cochrane Headline outcomes only
RR 1.38 [0.73, 2.62]
8 studies · 603 participants
Low

Early discontinuation of antibiotic treatment vs treatment until neutropenia resolution

Clinical failure · febrile neutropenia

It is very uncertain whether early discontinuation of antibiotic treatment changes clinical failure compared with treatment until neutropenia resolution (very low certainty).

1 finding from 1 review

Early discontinuation of antibiotics for febrile neutropenia versus continuation until neutropenia resolution in… 2019 · Cochrane Headline outcomes only
RR 1.23 [0.85, 1.77]
7 studies · 645 participants
Very low

Early discontinuation of antibiotic treatment vs treatment until neutropenia resolution

Bacteraemia · febrile neutropenia

It is very uncertain whether early discontinuation of antibiotic treatment changes any bacteraemia compared with treatment until neutropenia resolution (very low certainty).

1 finding from 1 review

Early discontinuation of antibiotics for febrile neutropenia versus continuation until neutropenia resolution in… 2019 · Cochrane Headline outcomes only
RR 1.56 [0.91, 2.66]
8 studies · 662 participants
Very low