What do systematic reviews say?

Early surgery vs late surgery

It is very uncertain whether early surgery changes complete recovery of facial nerve function at 12 months Defined as:… compared with late surgery (very low certainty).

• Surgical interventions for the early management of Bell's palsy 2021 · Cochrane Headline outcomes only
  RR 0.47 [0.03, 6.6]
  1 study · 26 participants
  Very low

Early surgery vs late surgery

• Surgical interventions for the early management of Bell's palsy 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 26 participants
  GRADE not reported

Early vs delayed mobilisation

• Interventions for treating proximal humeral fractures in adults 2022 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 259 participants
  Very low

Early vs late drain removal following pancreatic surgery

It is very uncertain whether early changes mortality compared with late drain removal following pancreatic surgery (very low certainty).

• Prophylactic abdominal drainage for pancreatic surgery 2021 · Cochrane Headline outcomes only
  RR 0.99 [0.06, 15.45]
  3 studies · 399 participants
  Very low
• Prophylactic abdominal drainage for pancreatic surgery 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Early vs late drain removal following pancreatic surgery

It is very uncertain whether early changes intra‐abdominal infection compared with late drain removal following pancreatic surgery (very low certainty).

• Prophylactic abdominal drainage for pancreatic surgery 2021 · Cochrane Headline outcomes only
  RR 0.44 [0.22, 0.89]
  2 studies · 285 participants
  Very low

Early vs late drain removal following pancreatic surgery

It is very uncertain whether early changes wound infection compared with late drain removal following pancreatic surgery (very low certainty).

• Prophylactic abdominal drainage for pancreatic surgery 2021 · Cochrane Headline outcomes only
  RR 1.32 [0.45, 3.85]
  2 studies · 285 participants
  Very low

Early vs late drain removal following pancreatic surgery

The review found no eligible studies for this question.

• Prophylactic abdominal drainage for pancreatic surgery 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Early vs late drain removal following pancreatic surgery

It is very uncertain whether early changes morbidity compared with late drain removal following pancreatic surgery (very low certainty).

• Prophylactic abdominal drainage for pancreatic surgery 2021 · Cochrane Headline outcomes only
  RR 0.49 [0.3, 0.81]
  2 studies · 258 participants
  Very low

Early vs late drain removal following pancreatic surgery

It is very uncertain whether early changes length of hospital stay compared with late drain removal following pancreatic surgery (very low certainty).

• Prophylactic abdominal drainage for pancreatic surgery 2021 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 399 participants
  Very low

Early enteral nutrition within 24 hours of lower gastrointestinal surgery vs later commencement

• Early enteral nutrition within 24 hours of lower gastrointestinal surgery versus later commencement for length of… 2019 · Cochrane Headline outcomes only
  no estimate extracted
  16 studies · 1346 participants
  Low

Early enteral nutrition within 24 hours of lower gastrointestinal surgery vs later commencement

• Early enteral nutrition within 24 hours of lower gastrointestinal surgery versus later commencement for length of… 2019 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 28 participants
  Low

Early enteral nutrition within 24 hours of lower gastrointestinal surgery vs later commencement

It is very uncertain whether early enteral nutrition within 24 hours of lower gastrointestinal… changes wound infection compared with later commencement (very low certainty).

• Early enteral nutrition within 24 hours of lower gastrointestinal surgery versus later commencement for length of… 2019 · Cochrane Headline outcomes only
  RR 0.99 [0.64, 1.52]
  12 studies · 1181 participants
  Very low

Early enteral nutrition within 24 hours of lower gastrointestinal surgery vs later commencement

Early enteral nutrition within 24 hours of lower gastrointestinal… showed no clear difference in intraabdominal abscess compared with later commencement (low certainty).

• Early enteral nutrition within 24 hours of lower gastrointestinal surgery versus later commencement for length of… 2019 · Cochrane Headline outcomes only
  RR 1 [0.26, 3.8]
  6 studies · 554 participants
  Low

Early enteral nutrition within 24 hours of lower gastrointestinal surgery vs later commencement

Early enteral nutrition within 24 hours of lower gastrointestinal… showed no clear difference in anastomotic leakage/dehiscence compared with later commencement (low certainty).

• Early enteral nutrition within 24 hours of lower gastrointestinal surgery versus later commencement for length of… 2019 · Cochrane Headline outcomes only
  RR 0.78 [0.38, 1.61]
  13 studies · 1232 participants
  Low

Early enteral nutrition within 24 hours of lower gastrointestinal surgery vs later commencement

Early enteral nutrition within 24 hours of lower gastrointestinal… showed no clear difference in pneumonia (within hospital stay) compared with later commencement (low certainty).

• Early enteral nutrition within 24 hours of lower gastrointestinal surgery versus later commencement for length of… 2019 · Cochrane Headline outcomes only
  RR 0.88 [0.32, 2.42]
  10 studies · 954 participants
  Low

Early enteral nutrition within 24 hours of lower gastrointestinal surgery vs later commencement

Early enteral nutrition within 24 hours of lower gastrointestinal… showed no clear difference in mortality compared with later commencement (low certainty).

• Early enteral nutrition within 24 hours of lower gastrointestinal surgery versus later commencement for length of… 2019 · Cochrane Headline outcomes only
  RR 0.56 [0.21, 1.52]
  12 studies · 1179 participants
  Low

Early enteral nutrition within 24 hours of lower gastrointestinal surgery vs later commencement

Early enteral nutrition within 24 hours of lower gastrointestinal… showed no clear difference in vomiting compared with later commencement (low certainty).

• Early enteral nutrition within 24 hours of lower gastrointestinal surgery versus later commencement for length of… 2019 · Cochrane Headline outcomes only
  RR 1.23 [0.96, 1.58]
  7 studies · 613 participants
  Low

Early enteral nutrition within 24 hours of lower gastrointestinal surgery vs later commencement

Early enteral nutrition within 24 hours of lower gastrointestinal… showed no clear difference in nausea compared with later commencement (low certainty).

• Early enteral nutrition within 24 hours of lower gastrointestinal surgery versus later commencement for length of… 2019 · Cochrane Headline outcomes only
  RR 0.95 [0.71, 1.26]
  2 studies · 118 participants
  Low

Early enteral nutrition within 24 hours of lower gastrointestinal surgery vs later commencement

It is very uncertain whether early enteral nutrition within 24 hours of lower gastrointestinal… changes nausea and vomiting compared with later commencement (very low certainty).

• Early enteral nutrition within 24 hours of lower gastrointestinal surgery versus later commencement for length of… 2019 · Cochrane Headline outcomes only
  RR 0.92 [0.6, 1.41]
  4 studies · 238 participants
  Very low

Summary of findings table 1: comparison of operation types: early results of needle fasciotomy vs limited fasciectomy

• Surgery for Dupuytren's contracture of the fingers 2015 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 57 participants
  Low