Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews · All outcomes

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No studies found 0 · 0%GRADE not reported 2 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Down syndrome vs Individuals without Down syndrome (healthy controls: siblings, schoolchildren or others)

Mean DMFT (decayed, missing, filled permanent teeth) · Individuals of all ages

Individuals with Down syndrome had a lower mean DMFT in permanent teeth than controls (pooled SMD -0.18, 95% CI -0.35 to -0.02; 6 studies; I2=20%); certainty of evidence not graded.

1 finding from 1 review

Association between Dental Caries and Down Syndrome: A Systematic Review and Meta-Analysis. 2015 All outcomes
Individuals with and without Down syndrome from referral centres, national databases and schools across China, Portugal, Jordan, Nigeria, Brazil and India; cross-sectional studies
SMD -0.18 [-0.35, -0.02]
6 studies · 718 participants
GRADE not reported

Down syndrome vs Individuals without Down syndrome (healthy controls: siblings, schoolchildren or others)

Dental caries · Individuals of all ages

Individuals with Down syndrome had a lower prevalence of dental caries than those without (pooled OR 0.36, 95% CI 0.22 to 0.57; 2 studies; I2=0%); certainty of evidence not graded.

1 finding from 1 review

Association between Dental Caries and Down Syndrome: A Systematic Review and Meta-Analysis. 2015 All outcomes
Individuals with and without Down syndrome in Portugal (reference centre, national database and closest-age siblings); cross-sectional studies
OR 0.36 [0.22, 0.57]
2 studies · 314 participants
GRADE not reported