Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

10 questions · 10 findings · 5 reviews

No studies found 1 · 10%GRADE not reported 1 · 10%Very low 3 · 30%Low 1 · 10%Moderate 3 · 30%High 1 · 10%

Dopamine agonist vs placebo

Risk for at least one adverse event per patient · patients with the treatment of cocaine dependence

Any dopamine agonist showed no clear difference in adverse events as N of participants with at least one adverse event compared with placebo (moderate certainty).

1 finding from 1 review

Dopamine agonist vs placebo

Withdrawals due to adverse events · patients with restless legs syndrome according to IRLSSG, 18 years or older

Summary of findings: dopamine agonists leads to higher number of dropouts due to adverse events compared with placebo (high certainty).

1 finding from 1 review

Dopamine agonist vs levodopa

Number of participants reporting an adverse event · patients with restless legs syndrome

Summary of findings: dopamine agonists showed no clear difference in number of patients experiencing adverse events compared with levodopa (moderate certainty).

1 finding from 1 review