Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

6 questions · 6 findings · 1 reviews · Hepato-Biliary

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 4 · 66.7%Low 2 · 33.3%Moderate 0 · 0%High 0 · 0%

Direct‐acting antivirals vs control

Proportion of participants with one or more serious adverse event at maximum · adults with chronic hepatitis C

It is very uncertain whether direct‐acting antivirals changes proportion of participants with one or more serious adverse event at… compared with control (very low certainty).

1 finding from 1 review

Direct‐acting antivirals vs control

Proportion of participants with no sustained virological response at maximum · adults with chronic hepatitis C

Direct‐acting antivirals may leads to lower proportion of participants with no sustained virological response at… compared with control (low certainty).

1 finding from 1 review

Direct‐acting antivirals withdrawn from the market vs control

Proportion of participants with one or more serious adverse event at maximum · adults with chronic hepatitis C

It is very uncertain whether direct‐acting antivirals withdrawn from the market changes proportion of participants with one or more serious adverse event at… compared with control (very low certainty).

1 finding from 1 review

Direct‐acting antivirals withdrawn from the market vs control

Proportion of participants with no sustained virological response at maximum · adults with chronic hepatitis C

Direct‐acting antivirals withdrawn from the market may leads to lower proportion of participants with no sustained virological response at… compared with control (low certainty).

1 finding from 1 review