Question · asked by 1 review

Direct‐acting antivirals withdrawn from the market vs control: Proportion of participants with no sustained virological response at maximum

Direct‐acting antivirals withdrawn from the market may leads to lower proportion of participants with no sustained virological response at… compared with control (low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Direct‐acting antivirals withdrawn from the market vs control
Proportion of participants with no sustained virological response at maximum · adults with chronic hepatitis C
Direct‐acting antivirals withdrawn from the market may leads to lower proportion of participants with no sustained virological response at… compared with control (low certainty).
Direct‐acting antivirals for chronic hepatitis C (2017) · Cochrane Headline outcomes only
RR 0.61 [0.55, 0.69]21 studies · 9075 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Direct‐acting antivirals for chronic hepatitis C
2017 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.