Pain resolution · patients with sore throat
Corticosteroids leads to higher complete resolution of pain at 24 hours compared with placebo (high certainty).
2 findings from 1 review
Time to initial pain relief (minutes) · patients with sore throat
1 finding from 1 review
Mean time to resolution of pain · patients with sore throat
1 finding from 1 review
Absolute reduction in pain measured by VAS · patients with sore throat
1 finding from 1 review
Adverse events · patients with sore throat
Corticosteroids showed no clear difference in adverse events compared with placebo (moderate certainty).
1 finding from 1 review
Recurrence · patients with sore throat
Corticosteroids showed no clear difference in recurrence/relapse rates compared with placebo (moderate certainty).
1 finding from 1 review
Days missed from work or school · patients with sore throat
1 finding from 1 review
Mortality ‐ adults · people with community‐acquired pneumonia
Corticosteroids probably leads to lower mortality ‐ adults compared with control (moderate certainty).
1 finding from 1 review
Mortality ‐ adults ‐ severe CAP · people with community‐acquired pneumonia
Corticosteroids probably leads to lower mortality ‐ adults ‐ severe CAP compared with control (moderate certainty).
1 finding from 1 review
Mortality ‐ adults ‐ non‐severe CAP · people with community‐acquired pneumonia
Corticosteroids showed no clear difference in mortality ‐ adults ‐ non‐severe CAP compared with control (moderate certainty).
1 finding from 1 review
Early clinical failure ‐ adults · people with community‐acquired pneumonia
Corticosteroids probably leads to lower early clinical failure ‐ adults compared with control (moderate certainty).
1 finding from 1 review
Early clinical failure ‐ adults ‐ severe CAP · people with community‐acquired pneumonia
Corticosteroids leads to lower early clinical failure ‐ adults ‐ severe CAP compared with control (high certainty).
1 finding from 1 review
Early clinical failure ‐ adults ‐ non‐severe CAP · people with community‐acquired pneumonia
Corticosteroids leads to lower early clinical failure ‐ adults ‐ non‐severe CAP compared with control (high certainty).
1 finding from 1 review
Early clinical failure ‐ children · people with community‐acquired pneumonia
Corticosteroids leads to lower early clinical failure ‐ children compared with control (high certainty).
1 finding from 1 review
Proportion of patients with resolution or improved symptoms at days 3 to 7 · patients with acute sinusitis
Oral corticosteroids probably leads to higher proportion of patients with resolution or improved symptoms at days… compared with placebo or NSAID (moderate certainty).
3 findings from 1 review
RR 1.33 [1.09, 1.62]
5 studies · 1043 participants
Moderate
RR 1.4 [1.08, 1.81]
4 studies · 869 participants
Low
RR 1.12 [0.87, 1.44]
1 study · 174 participants
Moderate
Proportion of patients with resolution or improved symptoms at days 4 to 14 · patients with acute sinusitis
Oral corticosteroids probably leads to higher proportion of patients with resolution or improved symptoms at days… compared with placebo or NSAID (moderate certainty).
2 findings from 1 review
Proportion of patients with resolution or improved symptoms at days 4 to 14 ‐ Co‐treatment with antibiotics · patients with acute sinusitis
Oral corticosteroids may leads to higher proportion of patients with resolution or improved symptoms at days… compared with placebo or NSAID (low certainty).
1 finding from 1 review
Adverse events · patients with acute sinusitis
1 finding from 1 review
Day 5 · children with acute otitis media
1 finding from 1 review
Day 14 · children with acute otitis media
1 finding from 1 review