Findings

What do systematic reviews say?

12 questions · 15 findings · 2 reviews · Oral Health

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No studies found 8 · 53.3%GRADE not reported 5 · 33.3%Very low 2 · 13.3%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Higher BMI (continuous / per-unit increment) vs Lower BMI (continuous reference / per 1 kg/m2 decrement)

Dental caries in children · Children (approx. 4-18 years)

Pooling studies that used BMI as a continuous variable showed no significant association between per-unit BMI and childhood dental caries (OR 1.01, 95% CI 0.99 to 1.03; I2=3.5%); ungraded.

3 findings from 1 review

Childhood obesity in relation to risk of dental caries: a cumulative and dose-response systematic review and… 2024 All outcomes
Dental examinations of children; 15 countries across Europe, Asia, the Americas and Oceania · Continuous BMI, direct pooling (studies reporting BMI as a continuous variable)
OR 1.01 [0.99, 1.03]
4 studies
GRADE not reported
Childhood obesity in relation to risk of dental caries: a cumulative and dose-response systematic review and… 2024 All outcomes
Dental examinations of children; 15 countries across Europe, Asia, the Americas and Oceania · Non-linear dose-response (restricted cubic splines)
Fig. 5: significant non-linear (restricted cubic spline) dose-response between BMI and childhood dental caries; relative risk rises at higher BMI (curve reaches ~2.4-2.9 at BMI 30-35) and is also elevated among…
Studies not reported
GRADE not reported
Childhood obesity in relation to risk of dental caries: a cumulative and dose-response systematic review and… 2024 All outcomes
Dental examinations of children; 15 countries across Europe, Asia, the Americas and Oceania · Linear dose-response (GLST, per 1 kg/m2 BMI increment)
OR 1.01 [1.00, 1.03]
16 studies
GRADE not reported

Low‐level laser therapy vs Placebo (sham) laser therapy

Patient-reported altered sensation (spontaneous or evoked: anaesthesia/paraesthesia/dysaesthesia/hyperalgesia/allodynia) · Patients of any age in any setting requiring intervention for iatrogenic injury to the inferior alveolar or lingual nerve

It is very uncertain whether low-level laser therapy (photon-plus GaAlAs diode laser; 70 mW… changes patient-reported altered sensation (spontaneous or evoked:… compared with placebo (sham) laser therapy (very low certainty).

2 findings from 1 review

Interventions for iatrogenic inferior alveolar and lingual nerve injury 2014 · Cochrane All outcomes
Lip
MD 21.79 [5.29, 38.29]
1 study · 13 participants
Very low
Interventions for iatrogenic inferior alveolar and lingual nerve injury 2014 · Cochrane All outcomes
Chin
MD 8.40 [3.67, 13.13]
1 study · 13 participants
Very low

Low‐level laser therapy vs Placebo (sham) laser therapy

Somatosensory evoked potentials · Patients of any age in any setting requiring intervention for iatrogenic injury to the inferior alveolar or lingual nerve

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for iatrogenic inferior alveolar and lingual nerve injury 2014 · Cochrane All outcomes
Results: 'No studies reported on ... somatosensory evoked potentials ...'. Not reported by the included trials.
0 studies
No studies found

Low‐level laser therapy vs Placebo (sham) laser therapy

Difficulty speaking · Patients of any age in any setting requiring intervention for iatrogenic injury to the inferior alveolar or lingual nerve

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for iatrogenic inferior alveolar and lingual nerve injury 2014 · Cochrane All outcomes
SoF row 'Difficulty speaking': This outcome was not reported in the included studies.
0 studies
No studies found

Low‐level laser therapy vs Placebo (sham) laser therapy

Difficulty eating · Patients of any age in any setting requiring intervention for iatrogenic injury to the inferior alveolar or lingual nerve

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for iatrogenic inferior alveolar and lingual nerve injury 2014 · Cochrane All outcomes
SoF row 'Difficulty eating': This outcome was not reported in the included studies.
0 studies
No studies found

Low‐level laser therapy vs Placebo (sham) laser therapy

Mechanosensory perception (load in grams to elicit sensation; Semmes Weinstein monofilaments) · Patients of any age in any setting requiring intervention for iatrogenic injury to the inferior alveolar or lingual nerve

Low-level laser therapy (photon-plus GaAlAs diode laser; 70 mW… led to higher mechanosensory perception (load in grams to elicit sensation; Semmes… compared with placebo (sham) laser therapy; GRADE not reported.

1 finding from 1 review

Interventions for iatrogenic inferior alveolar and lingual nerve injury 2014 · Cochrane All outcomes
MD 1.07 [0.17, 1.97]
2 studies · 26 participants
GRADE not reported

Low‐level laser therapy vs Placebo (sham) laser therapy

Quality of life · Patients of any age in any setting requiring intervention for iatrogenic injury to the inferior alveolar or lingual nerve

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for iatrogenic inferior alveolar and lingual nerve injury 2014 · Cochrane All outcomes
Results: 'No studies reported on quality of life ...'. Not reported by the included laser trials.
0 studies
No studies found

Low‐level laser therapy vs Placebo (sham) laser therapy

Adverse events · Patients of any age in any setting requiring intervention for iatrogenic injury to the inferior alveolar or lingual nerve

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for iatrogenic inferior alveolar and lingual nerve injury 2014 · Cochrane All outcomes
SoF row 'Adverse events': This outcome was not reported in the included studies.
0 studies
No studies found

Low‐level laser therapy vs Placebo (sham) laser therapy

Pain · Patients of any age in any setting requiring intervention for iatrogenic injury to the inferior alveolar or lingual nerve

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for iatrogenic inferior alveolar and lingual nerve injury 2014 · Cochrane All outcomes
SoF row 'Pain': This outcome was not reported in the included studies.
0 studies
No studies found

Low‐level laser therapy vs Placebo (sham) laser therapy

Taste · Patients of any age in any setting requiring intervention for iatrogenic injury to the inferior alveolar or lingual nerve

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for iatrogenic inferior alveolar and lingual nerve injury 2014 · Cochrane All outcomes
SoF row 'Taste': This outcome was not reported in the included studies.
0 studies
No studies found

Low‐level laser therapy vs Placebo (sham) laser therapy

Thermosensory (thermal) perception · Patients of any age in any setting requiring intervention for iatrogenic injury to the inferior alveolar or lingual nerve

Low-level laser therapy (photon-plus GaAlAs diode laser; 70 mW… showed no clear difference in thermosensory (thermal) perception compared with placebo (sham) laser therapy; GRADE not reported.

1 finding from 1 review

Interventions for iatrogenic inferior alveolar and lingual nerve injury 2014 · Cochrane All outcomes
MD 1.79 [-2.04, 5.62]
2 studies · 25 participants
GRADE not reported

Low‐level laser therapy vs Placebo (sham) laser therapy

Patient satisfaction · Patients of any age in any setting requiring intervention for iatrogenic injury to the inferior alveolar or lingual nerve

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for iatrogenic inferior alveolar and lingual nerve injury 2014 · Cochrane All outcomes
Results: no included study reported quality of life or patient satisfaction. In PUB2 patient satisfaction is merged with quality of life as 'quality of life/patient satisfaction'.
0 studies
No studies found