Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

24 questions · 32 findings · 3 reviews · Headline outcomes only

No studies found 5 · 15.6%GRADE not reported 0 · 0%Very low 13 · 40.6%Low 6 · 18.8%Moderate 8 · 25%High 0 · 0%

Combined oral contraceptive pill vs placebo or no treatment

Self‐reported pain (dysmenorrhoea) at the end of treatment (continuous data): dysmenorrhoea at 6 months' · women with endometriosis
2 findings from 1 review

Combined oral contraceptive pill vs any other medical treatment

Self‐reported pain (dysmenorrhoea) at the end of treatment (continuous data): dysmenorrhoea at 6 months' · women with endometriosis
2 findings from 1 review

Combined oral contraceptive pill vs any other medical treatment

Self‐reported pain (dysmenorrhoea) (dichotomous data) ‐ reduction of pain to zero at 6 months' · women with endometriosis

It is very uncertain whether combined oral contraceptive pill changes self‐reported pain (dysmenorrhoea) (dichotomous data): reduction of… compared with other medical treatment (very low certainty).

2 findings from 1 review

Combined oral contraceptive pill vs no pretreatment

Live birth or ongoing pregnancy · women undergoing assisted reproduction

Combined oral contraceptive pill probably leads to lower live birth or ongoing pregnancy (COCP + Ant vs Ant) compared with no pretreatment (moderate certainty).

2 findings from 1 review

Combined oral contraceptive pill vs no pretreatment

Pregnancy loss · women undergoing assisted reproduction

Combined oral contraceptive pill showed no clear difference in pregnancy loss (COCP + Ant vs Ant) compared with no pretreatment (moderate certainty).

2 findings from 1 review

Combined oral contraceptive pill vs no pretreatment

Multiple pregnancy rate · women undergoing assisted reproduction

Combined oral contraceptive pill showed no clear difference in multiple pregnancy rate (COCP + Ant vs Ant) compared with no pretreatment (low certainty).

2 findings from 1 review

Combined oral contraceptive pill vs no pretreatment

OHSS · women undergoing assisted reproduction

Combined oral contraceptive pill showed no clear difference in OHSS rate (COCP + Ant vs Ant) compared with no pretreatment (low certainty).

2 findings from 1 review

Combined oral contraceptive pill vs levonorgestrel intrauterine system

Adverse effects ‐ Any adverse events · heavy menstrual bleeding

It is very uncertain whether combined oral contraceptive pill changes adverse effects ‐ Any adverse events compared with levonorgestrel‐releasing intrauterine system (very low certainty).

1 finding from 1 review