All‐cause mortality during hospital stay · neonates with mechanical ventilation
Clonidine showed no clear difference in all‐cause mortality during initial hospitalization compared with placebo (low certainty).
1 finding from 1 review
aOne study and few events · neonates with mechanical ventilation
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Treatment failure To discharge · newborn infants with opioid withdrawal
It is very uncertain whether clonidine and opioid changes treatment failure To discharge compared with opioid alone (very low certainty).
1 finding from 1 review
Seizures To discharge · newborn infants with opioid withdrawal
It is very uncertain whether clonidine and opioid changes seizures To discharge compared with opioid alone (very low certainty).
1 finding from 1 review
Mortality after discharge (1‐3 months) · newborn infants with opioid withdrawal
It is very uncertain whether clonidine and opioid changes mortality post discharge compared with opioid alone (very low certainty).
1 finding from 1 review
Neurodevelopmental disability · newborn infants with opioid withdrawal
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Length of hospital stay · newborn infants with opioid withdrawal
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Days' pharmacological treatment · newborn infants with opioid withdrawal
1 finding from 1 review
Adverse events (treatment related) To discharge · newborn infants with opioid withdrawal
It is very uncertain whether clonidine and opioid changes adverse events (treatment related) To discharge compared with opioid alone (very low certainty).
1 finding from 1 review
Treatment failure To discharge · newborn infants with opioid withdrawal
It is very uncertain whether clonidine and opioid changes treatment failure To discharge compared with phenobarbital and opioid (very low certainty).
1 finding from 1 review
Seizures To discharge · newborn infants with opioid withdrawal
It is very uncertain whether clonidine and opioid changes seizures To discharge compared with phenobarbital and opioid (very low certainty).
1 finding from 1 review
Mortality before hospital discharge · newborn infants with opioid withdrawal
1 finding from 1 review
Neurodevelopmental disability · newborn infants with opioid withdrawal
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Length of hospital stay · newborn infants with opioid withdrawal
1 finding from 1 review
Days' pharmacological treatment · newborn infants with opioid withdrawal
1 finding from 1 review
Adverse events (treatment related) To discharge · newborn infants with opioid withdrawal
It is very uncertain whether clonidine and opioid changes adverse events (treatment related) To discharge compared with phenobarbital and opioid (very low certainty).
1 finding from 1 review