Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

19 questions · 19 findings · 3 reviews

No studies found 6 · 31.6%GRADE not reported 0 · 0%Very low 7 · 36.8%Low 3 · 15.8%Moderate 2 · 10.5%High 1 · 5.3%

Cervical cerclage in combination with antibiotics and tocolytics vs cervical cerclage

Serious neonatal morbidity

It is very uncertain whether cervical cerclage in combination with antibiotics and tocolytics changes serious neonatal morbidity (Reported in Miller 2014 as 'composite… compared with cervical cerclage alone (very low certainty).

1 finding from 1 review

Cervical cerclage in combination with antibiotics and tocolytics vs cervical cerclage

Perinatal loss: all ‐ including miscarriages and stillbirth (Note: data not available for neonatal death)

It is very uncertain whether cervical cerclage in combination with antibiotics and tocolytics changes perinatal loss: all ‐ including miscarriages and stillbirth (Note:… compared with cervical cerclage alone (very low certainty).

1 finding from 1 review

Cervical cerclage in combination with antibiotics and tocolytics vs cervical cerclage

Preterm birth less than 34 weeks' gestation

It is very uncertain whether cervical cerclage in combination with antibiotics and tocolytics changes preterm birth < 34 completed weeks of pregnancy compared with cervical cerclage alone (very low certainty).

1 finding from 1 review

Intrauterine balloon tamponade (latex balloon inflated with air) plus cerclage and normal care vs normal care

Hysterectomy to control bleeding · women with PPH, due to atony, following vaginal birth at home or in hospital (Soltan 2007)

It is very uncertain whether intrauterine balloon tamponade (latex balloon inflated with air)… changes hysterectomy to control bleeding compared with normal care (very low certainty).

1 finding from 1 review

Intrauterine balloon tamponade (latex balloon inflated with air) plus cerclage and normal care vs normal care

Serious maternal morbidity (renal or respiratory failure, cardiac arrest or multiple organ failure) · women with PPH, due to atony, following vaginal birth at home or in hospital (Soltan 2007)

The review found no eligible studies for this question.

1 finding from 1 review

Intrauterine balloon tamponade (latex balloon inflated with air) plus cerclage and normal care vs normal care

Number of women with total blood loss 1000 mL or more after randomisation · women with PPH, due to atony, following vaginal birth at home or in hospital (Soltan 2007)

The review found no eligible studies for this question.

1 finding from 1 review

Intrauterine balloon tamponade (latex balloon inflated with air) plus cerclage and normal care vs normal care

Blood transfusion (red cell or whole blood) · women with PPH, due to atony, following vaginal birth at home or in hospital (Soltan 2007)

The review found no eligible studies for this question.

1 finding from 1 review