Findings

What do systematic reviews say?

8 questions · 8 findings · 1 reviews · Headline outcomes only

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No studies found 0 · 0%GRADE not reported 4 · 50%Very low 2 · 25%Low 2 · 25%Moderate 0 · 0%High 0 · 0%

Carbamazepine vs placebo

Benzodiazepine discontinuation, end of intervention · adults who withdraw from chronic benzodiazepine use

Carbamazepine showed no clear difference in benzodiazepine discontinuation, end of intervention compared with placebo (low certainty).

1 finding from 1 review

Pharmacological interventions for benzodiazepine discontinuation in chronic benzodiazepine users 2018 · Cochrane Headline outcomes only
RR 1.33 [0.99, 1.8]
3 studies · 147 participants
Low

Carbamazepine vs tricyclic antidepressants (TCAs)

Benzodiazepine discontinuation, end of intervention · adults who withdraw from chronic benzodiazepine use

Carbamazepine showed no clear difference in benzodiazepine discontinuation, end of intervention compared with tricyclic antidepressant (low certainty).

1 finding from 1 review

Pharmacological interventions for benzodiazepine discontinuation in chronic benzodiazepine users 2018 · Cochrane Headline outcomes only
RR 1 [0.78, 1.29]
1 study · 48 participants
Low

Carbamazepine vs tricyclic antidepressants (TCAs)

Benzodiazepine discontinuation, longest · adults who withdraw from chronic benzodiazepine use

1 finding from 1 review

Pharmacological interventions for benzodiazepine discontinuation in chronic benzodiazepine users 2018 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Carbamazepine vs placebo

Benzodiazepine discontinuation, longest · adults who withdraw from chronic benzodiazepine use

It is very uncertain whether carbamazepine changes benzodiazepine discontinuation, longest compared with placebo (very low certainty).

1 finding from 1 review

Pharmacological interventions for benzodiazepine discontinuation in chronic benzodiazepine users 2018 · Cochrane Headline outcomes only
RR 1.41 [0.86, 2.29]
1 study · 40 participants
Very low

Carbamazepine vs tricyclic antidepressants (TCAs)

Benzodiazepine withdrawal symptoms, end of intervention · adults who withdraw from chronic benzodiazepine use

1 finding from 1 review

Pharmacological interventions for benzodiazepine discontinuation in chronic benzodiazepine users 2018 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Carbamazepine vs tricyclic antidepressants (TCAs)

Benzodiazepine withdrawal symptoms, longest · adults who withdraw from chronic benzodiazepine use

1 finding from 1 review

Pharmacological interventions for benzodiazepine discontinuation in chronic benzodiazepine users 2018 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Carbamazepine vs placebo

Benzodiazepine withdrawal symptoms, end of intervention · adults who withdraw from chronic benzodiazepine use

1 finding from 1 review

Pharmacological interventions for benzodiazepine discontinuation in chronic benzodiazepine users 2018 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 76 participants
Very low

Carbamazepine vs placebo

Benzodiazepine withdrawal symptoms, longest · adults who withdraw from chronic benzodiazepine use

1 finding from 1 review

Pharmacological interventions for benzodiazepine discontinuation in chronic benzodiazepine users 2018 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported