Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

29 questions · 32 findings · 7 reviews

No studies found 7 · 21.9%GRADE not reported 5 · 15.6%Very low 4 · 12.5%Low 7 · 21.9%Moderate 9 · 28.1%High 0 · 0%

Capsaicin vs placebo

Resolution of symptoms · non‐allergic rhinitis

Capsaicin may leads to higher daily record chart symptom resolution 4 weeks post‐treatment… compared with placebo (low certainty).

1 finding from 1 review

Capsaicin vs placebo

Treatment‐related adverse events · non‐allergic rhinitis

The review found no eligible studies for this question.

1 finding from 1 review

Capsaicin vs budesonide

Nasal obstruction during the 4th week of treatment Number of responders · patients with non‐allergic rhinitis

Capsaicin showed no clear difference in nasal obstruction during the 4th week of treatment Number of… compared with budesonide (low certainty).

1 finding from 1 review

Capsaicin vs budesonide

Treatment‐related adverse events · patients with non‐allergic rhinitis

The review found no eligible studies for this question.

1 finding from 1 review

High‐concentration (8%) capsaicin patch vs control patch (0.4%)

Patient Global Impression of Change much or very much improved · adults with postherpetic neuralgia
2 findings from 1 review

Summary of findings table ‐ Topical capsaicin vs placebo

Withdrawals due to adverse events · Adult patients aged >=18 years, clinically or radiographically diagnosed with TMD (McNeill 1997 criteria); moderate to severe pain of…
1 finding from 1 review

Summary of findings table ‐ Topical capsaicin vs placebo

Pain on daily activity (VAS) · Adult patients aged >=18 years, clinically or radiographically diagnosed with TMD (McNeill 1997 criteria); moderate to severe pain of…

Topical capsaicin (0.025% cream) showed no clear difference in pain on daily activity (VAS) compared with placebo; GRADE not reported.

1 finding from 1 review

Summary of findings table ‐ Topical capsaicin vs placebo

Maximum pain while on medication (VAS) · Adult patients aged >=18 years, clinically or radiographically diagnosed with TMD (McNeill 1997 criteria); moderate to severe pain of…

Topical capsaicin (0.025% cream) showed no clear difference in maximum pain while on medication (VAS) compared with placebo; GRADE not reported.

1 finding from 1 review