Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

335 questions · 350 findings · 37 reviews

No studies found 69 · 19.7%GRADE not reported 45 · 12.9%Very low 92 · 26.3%Low 114 · 32.6%Moderate 30 · 8.6%High 0 · 0%

Cognitive behavioural therapy as vs standard‐of‐care therapy

Reduction in physical signs Decrease in seizure frequency End of treatment · people with conversion disorder according to DSM‐IV or ICD‐10 criteria

It is very uncertain whether cognitive behavioural therapy as changes reduction in physical signs Reduction in monthly seizure frequency… compared with standard medical care (very low certainty).

2 findings from 1 review

Cognitive behavioural therapy as vs standard‐of‐care therapy

Reduction in physical sign Seizure freedom as assessed by a daily self‐reported seizure diary End of treatment · people with conversion disorder according to DSM‐IV or ICD‐10 criteria

It is very uncertain whether cognitive behavioural therapy as changes reduction in physical sign Seizure freedom as assessed by a daily… compared with standard medical care (very low certainty).

1 finding from 1 review

CBT vs alternative treatment

Reduction in pain intensity · People aged 12 years and over with painful TMD lasting 3 months or longer

Cognitive behavioural therapy (CBT) showed no clear difference in pain intensity at treatment completion compared with alternative (active) treatment (e.g. oral splint, medication,… (low certainty).

2 findings from 1 review

CBT vs alternative treatment

Mental distress · People aged 12 years and over with painful TMD lasting 3 months or longer

Cognitive behavioural therapy (CBT) may leads to lower psychological distress at follow-up compared with alternative (active) treatment (e.g. oral splint, medication,… (low certainty).

2 findings from 1 review

CBT vs inactive control (usual care care, attention control, waitlist)

Adverse events · People aged 12 years and over with painful TMD lasting 3 months or longer
1 finding from 1 review
  • Only 1 study reported adverse events as an outcome (Litt 2010): it found worsening symptoms in 13 people treated with an oral splint (as part of standard treatment) and 4 people treated with CBT.
    1 study · 101 participants
    Very low