Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

479 questions · 510 findings · 52 reviews

No studies found 99 · 19.4%GRADE not reported 64 · 12.5%Very low 144 · 28.2%Low 146 · 28.6%Moderate 57 · 11.2%High 0 · 0%

Comparison 1: Individual CBT‐based psychotherapy vs TAU or another comparator

Repetition of SH at post‐intervention · self‐harm in children and adolescents (up to 18 years or age)

Comparison 1: Individual CBT‐based psychotherapy showed no clear difference in repetition of SH by post‐intervention compared with TAU or other comparator (low certainty).

1 finding from 1 review

Comparison 1.2: Group‐based CBT‐based psychotherapy vs TAU or another comparator

Repetition of SH at post‐intervention · self‐harm in adults

Comparison 1.2: Group‐based CBT‐based psychotherapy showed no clear difference in repetition of SH at post‐intervention compared with TAU or another comparator (moderate certainty).

1 finding from 1 review

PHASE SPECIFIC TREATMENT (RISPERIDONE + CBT) + SPECIALISED TEAM vs SPECIALISED TEAM

Progression to psychosis ‐ by 12 months · people with psychosis

PHASE SPECIFIC TREATMENT (RISPERIDONE + CBT) + SPECIALISED TEAM probably leads to lower progression to psychosis ‐ by 6 months compared with SPECIALISED TEAM (moderate certainty).

2 findings from 1 review

Subacute to Chronic WAD: Trunk/Extremity Stretch/ROM + Trunk/Extremity Strengthening + Trunk/Extremity Endurance Training + Pattern/Synchronization: Coordination + Cardiovascular/Aerobic + Cognitive (CBT) + ANOTHER TREATMENT vs THAT SAME OTHER TREATMENT

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · patients with subacute/chronic WAD

Subacute to Chronic WAD: Trunk/Extremity Stretch/ROM +… showed no clear difference in pain Intensity: VAS 0 no pain to 10 worst pain ( compared with THAT SAME OTHER TREATMENT (low certainty).

1 finding from 1 review

Subacute to Chronic WAD: Trunk/Extremity Stretch/ROM + Trunk/Extremity Strengthening + Trunk/Extremity Endurance Training + Pattern/Synchronization: Coordination + Cardiovascular/Aerobic + Cognitive (CBT) + ANOTHER TREATMENT vs THAT SAME OTHER TREATMENT

Function: NDI 0 no disability to 50 maximum disability ( · patients with subacute/chronic WAD

Subacute to Chronic WAD: Trunk/Extremity Stretch/ROM +… showed no clear difference in function: NDI 0 no disability to 50 maximum disability ( compared with THAT SAME OTHER TREATMENT (low certainty).

1 finding from 1 review

Subacute to Chronic WAD: Trunk/Extremity Stretch/ROM + Trunk/Extremity Strengthening + Trunk/Extremity Endurance Training + Pattern/Synchronization: Coordination + Cardiovascular/Aerobic + Cognitive (CBT) + ANOTHER TREATMENT vs THAT SAME OTHER TREATMENT

Global Perceived Effect · patients with subacute/chronic WAD

Subacute to Chronic WAD: Trunk/Extremity Stretch/ROM +… showed no clear difference in global perceived effect: ‐5 to 5 scale; vastly worse to completely… compared with THAT SAME OTHER TREATMENT (low certainty).

1 finding from 1 review

Subacute to Chronic WAD: Trunk/Extremity Stretch/ROM + Trunk/Extremity Strengthening + Trunk/Extremity Endurance Training + Pattern/Synchronization: Coordination + Cardiovascular/Aerobic + Cognitive (CBT) + ANOTHER TREATMENT vs THAT SAME OTHER TREATMENT

QoL · patients with subacute/chronic WAD

Subacute to Chronic WAD: Trunk/Extremity Stretch/ROM +… showed no clear difference in quality of Life: SF‐36 0 high disability to 100 no disability ( compared with THAT SAME OTHER TREATMENT (low certainty).

1 finding from 1 review