Findings

What do systematic reviews say?

3 questions · 3 findings · 1 reviews · Drugs and Alcohol

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 3 · 100%High 0 · 0%

Buprenorphine vs clonidine

Drop‐out (end of treatment) · patients with opiate dependent adolescents

Buprenorphine showed no clear difference in drop out Number of participants who did not complete the… compared with clonidine (moderate certainty).

1 finding from 1 review

Detoxification treatments for opiate dependent adolescents 2014 · Cochrane Headline outcomes only
RR 0.45 [0.2, 1.04]
1 study · 36 participants
Moderate

Buprenorphine vs clonidine

Withdrawal symptoms · patients with opiate dependent adolescents

1 finding from 1 review

Detoxification treatments for opiate dependent adolescents 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 32 participants
Moderate

Buprenorphine vs clonidine

Initiation of naltrexone treatment Number of participants initiating naltrexone · patients with opiate dependent adolescents

Buprenorphine probably leads to higher initiation of naltrexone treatment Number of participants initiating… compared with clonidine (moderate certainty).

1 finding from 1 review

Detoxification treatments for opiate dependent adolescents 2014 · Cochrane Headline outcomes only
RR 11 [1.58, 76.55]
1 study · 36 participants
Moderate