Findings

What do systematic reviews say?

6 questions · 6 findings · 1 reviews · Neonatal

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No studies found 1 · 16.7%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 16.7%Moderate 1 · 16.7%High 3 · 50%

Bovine lung lavage surfactant extract vs modified bovine minced lung surfactant extract

Death or oxygen requirement at 36 weeks' postmenstrual age · Preterm infants for treatment of RDS

Bovine lung lavage surfactant extract showed no clear difference in death or oxygen requirement at 36 weeks' postmenstrual age compared with modified bovine minced lung surfactant extract (high certainty).

1 finding from 1 review

Comparison of animal‐derived surfactants for the prevention and treatment of respiratory distress syndrome in preterm… 2015 · Cochrane Headline outcomes only
RR 0.95 [0.86, 1.06]
3 studies · 2009 participants
High

Bovine lung lavage surfactant extract vs porcine minced lung surfactant extract

Oxygen requirement at 36 weeks' postmenstrual age · Preterm infants for treatment of RDS

Bovine lung lavage surfactant extract showed no clear difference in oxygen requirement at 36 weeks' postmenstrual age compared with porcine minced lung surfactant extract (low certainty).

1 finding from 1 review

Comparison of animal‐derived surfactants for the prevention and treatment of respiratory distress syndrome in preterm… 2015 · Cochrane Headline outcomes only
RR 0.75 [0.19, 3.04]
1 study · 54 participants
Low

Bovine lung lavage surfactant extract vs porcine minced lung surfactant extract

Death or oxygen requirement at 36 weeks' postmenstrual age · Preterm infants for treatment of RDS

The review found no eligible studies for this question.

1 finding from 1 review

Comparison of animal‐derived surfactants for the prevention and treatment of respiratory distress syndrome in preterm… 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Bovine lung lavage surfactant extract vs modified bovine minced lung surfactant extract

Oxygen requirement at 36 weeks' postmenstrual age · Preterm infants for prevention of RDS

Bovine lung lavage surfactant extract showed no clear difference in oxygen requirement at 36 weeks' postmenstrual age compared with modified bovine minced lung surfactant extract (moderate certainty).

1 finding from 1 review

Comparison of animal‐derived surfactants for the prevention and treatment of respiratory distress syndrome in preterm… 2015 · Cochrane Headline outcomes only
RR 0.97 [0.79, 1.19]
1 study · 749 participants
Moderate

Bovine lung lavage surfactant extract vs modified bovine minced lung surfactant extract

Death or oxygen requirement at 36 weeks' postmenstrual age · Preterm infants for prevention of RDS

1 finding from 1 review

Comparison of animal‐derived surfactants for the prevention and treatment of respiratory distress syndrome in preterm… 2015 · Cochrane Headline outcomes only
RR 1.02 [0.89, 1.17]
2 studies · 1133 participants
High

Bovine lung lavage surfactant extract vs modified bovine minced lung surfactant extract

Oxygen requirement at 36 weeks' postmenstrual age · Preterm infants for treatment of RDS

Bovine lung lavage surfactant extract showed no clear difference in oxygen requirement at 36 weeks' postmenstrual age (all infants) compared with modified bovine minced lung surfactant extract (high certainty).

1 finding from 1 review

Comparison of animal‐derived surfactants for the prevention and treatment of respiratory distress syndrome in preterm… 2015 · Cochrane Headline outcomes only
RR 0.95 [0.82, 1.11]
5 studies · 1564 participants
High