Global impression ‐ need for additional medication ‐ medium term Number of participants requiring additional medication · psychosis‐induced aggression or agitation
Benzodiazepines + antipsychotics showed no clear difference in global state: need for additional medication ‐ + haloperidol ‐… compared with same enzodiazepines (low certainty).
1 finding from 1 review
Adverse effects: any observed extrapyramidal symptoms ‐ short term (up to 6 months) · psychosis‐induced aggression or agitation
Benzodiazepines + antipsychotics showed no clear difference in adverse effects/events: extrapyramidal symptoms ‐ + haloperidol ‐… compared with same enzodiazepines (low certainty).
1 finding from 1 review
Satisfaction with treatment: from the perspective of consumer, family and informal carers or professionals/carers at any point during the acute management stage · psychosis‐induced aggression or agitation
1 finding from 1 review
Cost‐effectiveness · psychosis‐induced aggression or agitation
1 finding from 1 review
Adverse effects: 1. Sedation · psychosis‐induced aggression or agitation
It is very uncertain whether benzodiazepines + antipsychotics changes tranquillisation or asleep: sedation ‐ medium term ‐ +/vs… compared with same antipsychotics (very low certainty).
1 finding from 1 review
Global state: no improvement ‐ medium termAs defined in each study · psychosis‐induced aggression or agitation
Benzodiazepines + antipsychotics showed no clear difference in global state: no improvement ‐ +/vs haloperidol ‐ medium term As… compared with same antipsychotics (low certainty).
1 finding from 1 review
Global impression ‐ need for additional medication ‐ medium term Number of participants requiring additional medication · psychosis‐induced aggression or agitation
1 finding from 1 review
Adverse effects/events ‐ extrapyramidal symptoms ‐ medium term Number of instances of extrapyramidal symptoms · psychosis‐induced aggression or agitation
Benzodiazepines + antipsychotics showed no clear difference in adverse effects/events: extrapyramidal symptoms ‐ +/vs haloperidol ‐… compared with same antipsychotics (low certainty).
1 finding from 1 review
Satisfaction with treatment: from the perspective of consumer, family and informal carers or professionals/carers at any point during the acute management stage · psychosis‐induced aggression or agitation
1 finding from 1 review
Cost‐effectiveness · psychosis‐induced aggression or agitation
1 finding from 1 review
No clinically important response to treatment ‐ short term · patients with schizophrenia
It is very uncertain whether BENZODIAZEPINES AS SOLE TREATMENT changes no clinically important response to treatment ‐ short term compared with PLACEBO (very low certainty).
1 finding from 1 review
Unacceptability of treatment (drop-outs / leaving study early) · patients with schizophrenia
It is very uncertain whether BENZODIAZEPINES AS SOLE TREATMENT changes leaving the study early due to any reason (overall acceptability of… compared with PLACEBO (very low certainty).
1 finding from 1 review
Adverse effects (drop‐outs due to adverse effects4) · patients with schizophrenia
1 finding from 1 review
Number of participants tranquillised at endpoint of the study (Desired sedation/tranquillisation) · patients with schizophrenia
The review found no eligible studies for this question.
1 finding from 1 review
Adverse effects: 1. Sedation · psychosis‐induced aggression or agitation
1 finding from 1 review
Global state: no improvement ‐ medium termAs defined in each study · psychosis‐induced aggression or agitation
1 finding from 1 review
Global state: need for additional medication ‐ medium term · psychosis‐induced aggression or agitation
1 finding from 1 review
Adverse effects/events ‐ extrapyramidal symptoms ‐ medium term Number of instances of extrapyramidal symptoms · psychosis‐induced aggression or agitation
1 finding from 1 review
Satisfaction with treatment: from the perspective of consumer, family and informal carers or professionals/carers at any point during the acute management stage · psychosis‐induced aggression or agitation
1 finding from 1 review
Cost‐effectiveness · psychosis‐induced aggression or agitation
1 finding from 1 review