Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

29 questions · 29 findings · 2 reviews · Cystic Fibrosis and Genetic Disorders

No studies found 10 · 34.5%GRADE not reported 0 · 0%Very low 6 · 20.7%Low 0 · 0%Moderate 10 · 34.5%High 3 · 10.3%

Inhaled tobramycin (TNS) plus oral azithromycin vs TNS plus oral placebo

Number experiencing adverse effects · children with cystic fibrosis and a new culture positive for P aeruginosa

Inhaled tobramycin (TNS) plus oral azithromycin showed no clear difference in adverse effects of antibiotics: number of participants experiencing… compared with TNS plus oral placebo (moderate certainty).

1 finding from 1 review