Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

16 questions · 16 findings · 1 reviews

No studies found 4 · 25%GRADE not reported 0 · 0%Very low 5 · 31.3%Low 5 · 31.3%Moderate 2 · 12.5%High 0 · 0%

Azelaic acid vs adapalene

Participants' global self‐assessment of acne improvement · participants with acne

It is very uncertain whether azelaic acid changes participants' global self‐assessment of acne improvement Improved to… compared with adapalene (very low certainty).

1 finding from 1 review

Azelaic acid vs tretinoin

Participants' global self‐assessment of acne improvement Good to excellent improvement (long term: treatment duration > 8 weeks) · participants with acne

Azelaic acid showed no clear difference in participants' global self‐assessment of acne improvement Good to… compared with tretinoin (moderate certainty).

1 finding from 1 review

Azelaic acid vs benzoyl peroxide

Participants' global self‐assessment of acne improvement Good or very good improvement (long term: treatment duration > 8 weeks) · participants with acne

Azelaic acid probably leads to lower participants' global self‐assessment of acne improvement Good or… compared with benzoyl peroxide (moderate certainty).

1 finding from 1 review

Azelaic acid vs clindamycin

Participants' global self‐assessment of acne improvement Good or very good improvement (long term: treatment duration > 8 weeks) · participants with acne

Azelaic acid showed no clear difference in participants' global self‐assessment of acne improvement Good or… compared with clindamycin (low certainty).

1 finding from 1 review