Findings

What do systematic reviews say?

8 questions · 8 findings · 1 reviews · Headline outcomes only

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No studies found 1 · 12.5%GRADE not reported 0 · 0%Very low 7 · 87.5%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Any intervention vs steroid alone or plus levofloxacin

Resolution of symptoms · epidemic keratoconjunctivitis

1 finding from 1 review

Topical pharmacologic interventions versus placebo for epidemic keratoconjunctivitis 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Any intervention vs steroid alone or plus levofloxacin

Proportion of participants with resolution of signs within 7 days of treatment (higher is favored) · epidemic keratoconjunctivitis

1 finding from 1 review

Topical pharmacologic interventions versus placebo for epidemic keratoconjunctivitis 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Any intervention vs steroid alone or plus levofloxacin

Proportion of eyes in which SEI had developed within 21 days of treatment (lower is favored) · epidemic keratoconjunctivitis

It is very uncertain whether any intervention changes proportion of eyes in which SEI had developed within 21 days of… compared with steroid alone or plus levofloxacin (very low certainty).

1 finding from 1 review

Topical pharmacologic interventions versus placebo for epidemic keratoconjunctivitis 2022 · Cochrane Headline outcomes only
RR 0.08 [0.01, 0.55]
2 studies · 69 participants
Very low

Any intervention vs steroid alone or plus levofloxacin

Proportion of participants in whose eyes SEI had disappeared within 21 days of treatment (higher is favored) · epidemic keratoconjunctivitis

1 finding from 1 review

Topical pharmacologic interventions versus placebo for epidemic keratoconjunctivitis 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Any intervention vs steroid alone or plus levofloxacin

Proportion of participants who discontinued medication and did not develop rebound SEI within 21 days (higher is favored) · epidemic keratoconjunctivitis

It is very uncertain whether any intervention changes proportion of participants who discontinued medication and did not… compared with steroid alone or plus levofloxacin (very low certainty).

1 finding from 1 review

Topical pharmacologic interventions versus placebo for epidemic keratoconjunctivitis 2022 · Cochrane Headline outcomes only
RR 1.04 [0.94, 1.14]
3 studies · 231 participants
Very low

Any intervention vs steroid alone or plus levofloxacin

Proportion of participants who had evidence of adenoviral eradication within 14 days of treatment (higher is favored) · epidemic keratoconjunctivitis

1 finding from 1 review

Topical pharmacologic interventions versus placebo for epidemic keratoconjunctivitis 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Any intervention vs steroid alone or plus levofloxacin

Proportion of initially unaffected fellow eyes that had signs/symptoms of infection within 7 days of onset of signs/symptoms in the first eye (lower is favored) · epidemic keratoconjunctivitis

The review found no eligible studies for this question.

1 finding from 1 review

Topical pharmacologic interventions versus placebo for epidemic keratoconjunctivitis 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Any intervention vs steroid alone or plus levofloxacin

Mean number of days from treatment initiation to resolution of symptoms or signs (shorter is favored) · epidemic keratoconjunctivitis

1 finding from 1 review

Topical pharmacologic interventions versus placebo for epidemic keratoconjunctivitis 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low