Antimicrobial photodynamic therapy (PDT) vs No photodynamic therapy (untreated negative control)
Microbial reduction (viable count, log CFU/mL) · Patients with dental caries (in vivo cariogenic microorganisms, including children with early childhood caries)
In randomized clinical trials, photodynamic therapy significantly reduced cariogenic microbial counts versus untreated control (SMD -1.16, 95% CI -2.02 to -0.30; 2 trials), but heterogeneity was high (I2=70%) and considered too high to rely on; certainty was not graded.
1 finding from 1 review
- Effect of Photodynamic Therapy on Microorganisms Responsible for Dental Caries: A Systematic Review and Meta-Analysis. 2019 All outcomesClinical (in vivo) · Randomized clinical trialsSMD -1.16 [-2.02, -0.30]2 studies · 42 participantsGRADE not reported