Findings

What do systematic reviews say?

2 questions · 2 findings · 2 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 50%Moderate 0 · 0%High 1 · 50%

Any antihypertensive drug vs placebo or no treatment

Total mortality Mean duration of 3.8 years · adults 60 years or older with primary hypertension

Antihypertensive drug leads to lower total mortality Mean duration of 3.8 years compared with placebo or no treatment (high certainty).

1 finding from 1 review

Pharmacotherapy for hypertension in adults 60 years or older 2019 · Cochrane Headline outcomes only
RR 0.91 [0.85, 0.97]
13 studies · 25932 participants
High

Antihypertensive drug therapy vs control

Cardiovascular mortality and morbidity Mean duration of 3.7 years · adults aged 18‐59 years with primary hypertension (mild to moderate systolic or diastolic hypertension)

Antihypertensive drug therapy may leads to lower total cardiovascular mortality + morbidity compared with control (low certainty).

1 finding from 1 review

Pharmacotherapy for hypertension in adults aged 18 to 59 years 2017 · Cochrane Headline outcomes only
RR 0.78 [0.67, 0.91]
6 studies · 17278 participants
Low