Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

8 questions · 8 findings · 1 reviews · ENT

No studies found 2 · 25%GRADE not reported 0 · 0%Very low 1 · 12.5%Low 4 · 50%Moderate 1 · 12.5%High 0 · 0%

Antihistamines vs placebo

Proportion of susceptible participants who did not experience any motion sickness symptoms under natural conditions Assessed by: self‐reported questionnaires6,7 · patients with motion sickness

Antihistamines probably leads to higher proportion of susceptible participants who did not experience any… compared with placebo (moderate certainty).

1 finding from 1 review

Antihistamines vs placebo

Proportion of susceptible participants who did not experience any motion sickness symptoms under experimental conditions Assessed by: calculated based on head movements tolerated (rotating chair); MSAQ · patients with motion sickness
1 finding from 1 review

Antihistamines vs placebo

Proportion of susceptible participants who experienced a reduction or resolution of existing motion sickness symptoms · patients with motion sickness

The review found no eligible studies for this question.

1 finding from 1 review

Antihistamines vs placebo

Physiological measures: heart rate and core temperature · patients with motion sickness

The review found no eligible studies for this question.

1 finding from 1 review

Antihistamines vs placebo

Adverse effects: 1. Sedation · patients with motion sickness

Antihistamines may leads to higher adverse effects: sedation Assessed by: adverse effect questionnaire… compared with placebo (low certainty).

1 finding from 1 review

Antihistamines vs placebo

Adverse effects: impaired cognition Assessed by: adverse effect questionnaire (presence or absence given numerical values) · patients with motion sickness

Antihistamines showed no clear difference in adverse effects: impaired cognition Assessed by: adverse effect… compared with placebo (low certainty).

1 finding from 1 review

Antihistamines vs placebo

Adverse effects ‐ Blurred vision No of patients with blurred vision · patients with motion sickness

Antihistamines showed no clear difference in adverse effects: blurred vision Assessed by: adverse effect… compared with placebo (low certainty).

1 finding from 1 review