Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

24 questions · 24 findings · 1 reviews · ENT

No studies found 11 · 45.8%GRADE not reported 0 · 0%Very low 6 · 25%Low 6 · 25%Moderate 1 · 4.2%High 0 · 0%

Antihistamines vs placebo

Proportion of susceptible participants who did not experience any motion sickness symptoms under natural conditions Assessed by: self‐reported questionnaires6,7 · patients with motion sickness

Antihistamines probably leads to higher proportion of susceptible participants who did not experience any… compared with placebo (moderate certainty).

1 finding from 1 review

Antihistamines vs scopolamine

Proportion of susceptible participants who experienced a reduction or resolution of existing motion sickness symptoms · patients with motion sickness

The review found no eligible studies for this question.

1 finding from 1 review

Antihistamines vs scopolamine

Physiological measures: core temperature and gastric tachyarrhythmia (electrogastrography) · patients with motion sickness

The review found no eligible studies for this question.

1 finding from 1 review

Antihistamines vs scopolamine

Adverse effects: 1. Sedation · patients with motion sickness

It is very uncertain whether antihistamines changes adverse effects: sedation Assessed by: self‐reported compared with scopolamine (very low certainty).

1 finding from 1 review

Antihistamines vs scopolamine

Adverse effects: impaired cognitive function · patients with motion sickness

The review found no eligible studies for this question.

1 finding from 1 review

Antihistamines vs antiemetics

Proportion of susceptible participants who did not experience any motion sickness symptoms under experimental conditions Assessed by: calculated based on head movements tolerated (rotating chair); MSAQ · patients with motion sickness
1 finding from 1 review

Antihistamines vs antiemetics

Proportion of susceptible participants who experienced a reduction or resolution of existing motion sickness symptoms · patients with motion sickness

The review found no eligible studies for this question.

1 finding from 1 review

Antihistamines vs antiemetics

Physiological measures: heart rate and core temperature · patients with motion sickness

The review found no eligible studies for this question.

1 finding from 1 review

Antihistamines vs placebo

Proportion of susceptible participants who did not experience any motion sickness symptoms under experimental conditions Assessed by: calculated based on head movements tolerated (rotating chair); MSAQ · patients with motion sickness
1 finding from 1 review

Antihistamines vs antiemetics

Adverse effects: impaired cognition and blurred vision · patients with motion sickness

The review found no eligible studies for this question.

1 finding from 1 review

Antihistamines vs acupuncture

Proportion of susceptible participants who did not experience any motion sickness symptoms under experimental conditions Assessed by: calculated based on head movements tolerated (rotating chair); MSAQ · patients with motion sickness

It is very uncertain whether antihistamines changes proportion of susceptible participants who did not experience any… compared with acupuncture (very low certainty).

1 finding from 1 review

Antihistamines vs acupuncture

Proportion of susceptible participants who experienced a reduction or resolution of existing motion sickness symptoms · patients with motion sickness

The review found no eligible studies for this question.

1 finding from 1 review

Antihistamines vs acupuncture

Physiological measures: heart rate, core temperature and gastric tachyarrhythmia (electrogastrography) · patients with motion sickness

The review found no eligible studies for this question.

1 finding from 1 review

Antihistamines vs acupuncture

Adverse effects: sedation, impaired cognitive function, blurred vision · patients with motion sickness

The review found no eligible studies for this question.

1 finding from 1 review

Antihistamines vs placebo

Proportion of susceptible participants who experienced a reduction or resolution of existing motion sickness symptoms · patients with motion sickness

The review found no eligible studies for this question.

1 finding from 1 review

Antihistamines vs placebo

Physiological measures: heart rate and core temperature · patients with motion sickness

The review found no eligible studies for this question.

1 finding from 1 review