Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

204 questions · 212 findings · 23 reviews

No studies found 49 · 23.1%GRADE not reported 3 · 1.4%Very low 70 · 33%Low 63 · 29.7%Moderate 25 · 11.8%High 2 · 0.9%

Antidepressants vs any other pharmacological intervention

Depression remission · women of any age, with PND up to 12 months

It is very uncertain whether antidepressants changes depression remission (acute phase, 5 ≤ 12 weeks) compared with any other pharmacological intervention (very low certainty).

2 findings from 1 review

Tricyclic antidepressants vs placebo

Clinical global impression (response rate) ‐ desipramine · Children and adolescents with ADHD

Tricyclic antidepressants (TCAs) may leads to higher clinical global impression (response rate) ‐ desipramine compared with placebo (low certainty).

1 finding from 1 review