Depression severity (acute phase, 5 ≤ 12 weeks) · patients with major depression
1 finding from 1 review
Depression severity: continuous phase (> 12 weeks) · patients with major depression
1 finding from 1 review
Acceptability ‐ total dropouts · patients with major depression
Antidepressants plus benzodiazepines showed no clear difference in acceptability of treatment (dropout for any reason) compared with antidepressants alone (moderate certainty).
1 finding from 1 review
Anxiety · patients with major depression
1 finding from 1 review
Adverse effects (dropouts) · patients with major depression
Antidepressants plus benzodiazepines probably leads to lower adverse effects (dropouts) compared with antidepressants alone (moderate certainty).
1 finding from 1 review
Quality of sleep · adults with insomnia
1 finding from 1 review
Adverse events · adults with insomnia
1 finding from 1 review
Sleep efficiency · adults with insomnia
1 finding from 1 review
Leaving the study early · adults with panic disorder
Tricyclic antidepressants probably leads to lower total number of dropouts compared with placebo (moderate certainty).
1 finding from 1 review
Failure to remit at endpoint · adults with panic disorder
Tricyclic antidepressants may leads to lower failure to remit compared with placebo (low certainty).
1 finding from 1 review
panic symptoms · adults with panic disorder
2 findings from 1 review
Withdrawals due to adverse events · adults with panic disorder
Tricyclic antidepressants probably leads to higher number of dropouts due to adverse effects compared with placebo (moderate certainty).
1 finding from 1 review
Outcomes (2‐6 months post‐treatment) · adults with panic disorder
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Failure to respond at endpoint (6‐12 weeks) · adults with panic disorder
Tricyclic antidepressants probably leads to lower failure to respond compared with placebo (moderate certainty).
1 finding from 1 review
Quality of sleep · adults with insomnia
1 finding from 1 review
Adverse events (at 4, 6 or 12 weeks) · adults with insomnia
Tricyclic antidepressants showed no clear difference in adverse events (at 4, 6 or 12 weeks) compared with placebo (low certainty).
1 finding from 1 review
Sleep onset latency ‐ not reported · adults with insomnia
1 finding from 1 review
Sleep efficiency · adults with insomnia
1 finding from 1 review
Total sleep time, next night; · adults with insomnia
1 finding from 1 review
Diabetes · Adults with mental disorders in low‐ and middle‐income countries
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found